R&D
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Job Title: Senior Scientist, Rare Blood Disorders and Vascular Inflammation

Location: Cambridge, MA

About the Job

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

We are seeking a Senior Scientist to drive the advancement of our research and development pipeline in Rare Blood Disorders, with a particular focus on vascular inflammation and its role in genetically driven conditions such as sickle cell disease. This role will also investigate how vascular dysfunction and coagulopathies contribute to brain health outcomes, including stroke and cognitive impairment, within the context of rare diseases. Beyond sickle cell, the candidate will also provide research expertise across a variety of other rare blood disorders to support Sanofi’s entire rare blood pipeline, including clinical assets and marketed products.

The successful candidate will play a key role in identifying novel therapeutic opportunities and expanding our pipeline into new indications. They will contribute across research, clinical, and business development efforts, helping to align scientific insights with strategic goals. This position offers a unique opportunity to shape the future of therapeutics for rare blood disorders and help deliver transformative treatments to patients worldwide.

About Sanofi:
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities:

• Leverage research expertise to drive pipeline expansion through external innovation—staying at the forefront of novel biology, shaping ideas, and enabling validation studies via hands-on lab work and partnerships with external collaborators or CROs

• Advance the clinical development pipeline by applying research expertise to drive therapeutic differentiation and uncover deeper insights into the mechanisms of action of key assets.

• Contribute to life cycle management efforts across all therapeutic programs, with a particular focus on rare bleeding disorders.

• Strengthen internal capabilities to explore the role of vascular inflammation in additional rare disorders and its impact on the CNS, while generating proposals for new targets and indications—with the potential to lead future preclinical programs.

About You

Qualifications

Basic Requirements

• Ph.D. in a scientific field, with 3+ years of relevant experience in industry or academia

• A degree in molecular/cellular biology or related field is preferred

• Strong background in translational research and drug development, preferably in the rare blood disorders field

• Proficiency in molecular, cellular, and biochemical techniques, assay development, and disease modeling

• Demonstrated ability to produce high-quality documentation and scientific presentations

• Proven track record of impactful contributions to research programs and publications

Preferred Experience

• Deep expertise in hematologic conditions—including sickle cell disease, vascular inflammation, cerebrovascular disorders such as stroke, and coagulopathies

• Familiarity and/or experience in other rare blood disorders (i.e. hemophilia, VWD, ITP, aTTP, PV, HHT)

• Proficient in designing and executing in vitro and in vivo pharmacology studies to investigate mechanisms of disease pathology and evaluate therapeutic efficacy, ideally including hands-on experience with relevant disease models for sickle cell, other rare blood disorders, and/or models of vascular inflammation

• Experience in overseeing CRO partnerships and cultivating academic collaborations to advance research and development objectives is preferred

• Experience working with business development is a plus

• Experience authoring regulatory documents to support IND or CTA applications, responding to inquiries from regulatory authorities, etc. is a plus

• Computational data analysis skills (e.g., R, Python) are a plus

Core Competencies

• Ability to weigh and integrate inputs and opinions from broad range of stakeholders with diverse backgrounds

• Ability to capture and distill complex data, concepts, and information into clear, well-articulated messages to guide and drive decision-making

• Excellent written and oral communication skills, with the ability to communicate effectively in multidisciplinary teams as well as to senior leadership

• Independent and resourceful with ability to navigate large organizations new challenges with results-oriented mindset

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.​​

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.​​

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.​

• ​Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.​

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discovery Extraordinary.

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