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Job Title: Chromatography Principal Scientist

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. 

Sanofi is seeking a highly motivated individual to join our analytical group as a Chromatography Principal Scientist. The group is part of the synthetic platform within Global CMC Development with focus on small molecules that is striving to become an industry leader in the development of transformative medicines.   

 The primary responsibility of this position is to provide analytical support to the chemistry teams and to develop analytical methods mainly on small molecules using equipment including HPLC, UHPLC, GC, and potentiometry.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

• Develop specific and robust analytical methods using equipment including HPLC, UHPLC, GC, and be responsible for validating the methods when necessary

• Analyze synthetic molecules mainly by HPLC/UHPLC, GC, potentiometry, and TLC.

• Perform quantification of impurities

• Perform mass balance studies

• Design and implement analytical strategies for synthesis intermediates and raw materials

• Develop effective collaborations with others within project teams and between analytical groups

• Generate technical reports independently

• Share knowledge and experience of analytical method development for synthetic molecules

• Introduce innovative analytical approaches to facilitate optimal decision-making.

• May serve as a project lead

About You

Basic Qualifications

• A Master’s degree or equivalent in Analytical Chemistry or related field with a minimum of 8ears, or a PhD with minimum of 5 years of experience in the pharmaceutical/biotech industry. A PhD in Analytical Chemistry is preferred.

• Expertise in the operation of LC and GC

• Familiarity with the operation of potentiometry titrator, and TLC from multiple manufacturers

• Extensive experiences in method development using HPLC/UPLC and GC

• Experiences in analytical method validation

• Record of adhering to and promoting lab safety practices

• Good communications skills

Preferred Qualifications

• In-depth understanding of the separation principles of LC, GC and method development software.

• Deep expertise in chromatography method development and trouble shoots

• Knowledge of QbD concepts, specification setting, and cGMP, with experience in contributing to regulatory submission

• Communicates effectively in individual and group settings and collaborate effectively in a multi-disciplinary team setting

• Demonstrated project management skills

• Consistent record of collaboration with scientists and other stakeholders at external enterprises

• Advanced scientific network in the industry and academia

• Record of patents and publications

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discovery Extraordinary.

Werde Teil von Sanofi und starte mit uns in eine neue Ära der Wissenschaft – wo dein persönliches Wachstum genauso wegweisend ist wie unsere Arbeit. Wir investieren in dich, damit du weiterkommst, schneller denkst und Dinge möglich machst, die vorher undenkbar waren. Du wirst Grenzen verschieben, Gewohntes hinterfragen und smarte Lösungen entwickeln, die direkt bei den Menschen ankommen, für die wir da sind. Bereit, die Wunder der Wissenschaft zu jagen und Leben zu verbessern? Dann lass uns gemeinsam Großes bewegen – und das Außergewöhnliche entdecken.

Bei Sanofi stehen allen die gleichen Chancen offen – unabhängig von Herkunft, Hautfarbe, Religion, Geschlecht, Nationalität, sexueller Orientierung, Alter, Staatsangehörigkeit, Familienstand, Behinderung, Geschlechtsidentität, Veteranenstatus oder anderen gesetzlich geschützten Merkmalen.