R&D
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Job Title: Senior Scientist - Cell Biology and Disease Modeling

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. 

Sanofi Intrépide Research Laboratories is an innovative initiative identifying and advancing breakthrough science, technology, and business opportunities critical to our pipeline strategy. Operating globally with sites in the US and China, we foster an entrepreneurial culture where scientific excellence drives decision-making. Our agile teams work collaboratively to accelerate the delivery of high-impact therapeutics through efficient execution and creative problem-solving.

Join our dynamic US Core Team to develop and implement cellular models that recapitulate human disease biology. This role combines hands-on cell biology expertise with strategic project leadership to accelerate therapeutic discovery through physiologically relevant disease models.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

• Internalize, design and/or establish in vitro and ex vivo cellular models that reflect aspects of human disease pathophysiology, with a focus on immune-mediated diseases, and use to evaluate therapeutic candidate efficacy and mechanism-of-action

• Implement advanced cell culture techniques including 3D cultures, co-cultures, and patient-derived systems, with multi-omic, imaging and other read-outs

• Establish and validate cellular biomarker assays for translational research applications

• Develop and maintain cell biology laboratory capabilities, including equipment procurement and protocol standardization

• Collaborate with CROs to implement and transfer cellular model protocols

• Interface cross-functionally with research teams to integrate cellular biology data into therapeutic development decisions

About You

Required Qualifications

• Bachelor's + 8 years of relevant experience OR

• Master's + 5 years of relevant experience OR

• Ph.D. + 3 years of relevant experience

• Relevant experience in biopharma is preferred

• 2+ years of biopharma industry experience in cellular model development

• Strong track record in establishing disease-relevant cellular systems

• Experience with multi-omics, cellular imaging, flow cytometry, and/or high-content analysis

• Project management experience including timeline and budget oversight

Preferred Qualifications

• Experience with primary human immune and other cells and/or iPSC-derived cellular models

• Familiarity with CRISPR gene editing for cellular model development

• Experience with microfluidic or organ-on-chip technologies

• Experience managing CRO relationships for cellular biology work

• Equipment procurement and cell biology lab setup experience

• Demonstrated scientific creativity in disease model development

• Experience with mechanistic in vivo models of disease

Core Competencies

• Deep understanding of cellular biology and human disease mechanisms

• Strong analytical and data interpretation skills

• Excellence in written and verbal communication of complex biological data

• Ability to work effectively in a fast-paced, collaborative environment

• Entrepreneurial mindset with calculated risk-taking ability

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

• Opportunity to shape the future of therapeutic discovery

• Highly collaborative, science-driven culture

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discovery Extraordinary.

Werde Teil von Sanofi und starte mit uns in eine neue Ära der Wissenschaft – wo dein persönliches Wachstum genauso wegweisend ist wie unsere Arbeit. Wir investieren in dich, damit du weiterkommst, schneller denkst und Dinge möglich machst, die vorher undenkbar waren. Du wirst Grenzen verschieben, Gewohntes hinterfragen und smarte Lösungen entwickeln, die direkt bei den Menschen ankommen, für die wir da sind. Bereit, die Wunder der Wissenschaft zu jagen und Leben zu verbessern? Dann lass uns gemeinsam Großes bewegen – und das Außergewöhnliche entdecken.

Bei Sanofi stehen allen die gleichen Chancen offen – unabhängig von Herkunft, Hautfarbe, Religion, Geschlecht, Nationalität, sexueller Orientierung, Alter, Staatsangehörigkeit, Familienstand, Behinderung, Geschlechtsidentität, Veteranenstatus oder anderen gesetzlich geschützten Merkmalen.