R&D
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Job Title: Senior Scientist, Systems Biology

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. 

The Systems Biology Cluster, part of the Target, Disease, and Systems Biology function at Sanofi Research, is dedicated to delivering first-in-class medicines to patients. Our approach involves deconstructing disease mechanisms into cellular building blocks to accelerate the Sanofi R&D pipeline through cell-centric analytical approaches.

We seek an exceptional Senior Scientist who demonstrates independence, proactivity, and strong organizational skills. The ideal candidate will possess expertise in developing and benchmarking ML/AI models (either cell-centric and/or multi-modal), as well as a solid biological foundation, to help build upon our current achievements and secure our future success. Experience leveraging high-content immunoscience-related chemical, genetic, or cytokine screens to train, tune and benchmark such ML/AI models is highly valued.  

The successful applicant will have the ability to creatively lead projects, coordinate scientific activities, summarize and present results, and establish their relevance to critical decision points in the drug discovery process. Additionally, there may be opportunities to mentor interns and junior scientists.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• Lead the development and application of ML/AI algorithms for virtual cell & disease model, especially geared to predict perturbations and functional synergy.

• Collaborate to build scalable analytical pipelines that integrate multi-modal data such as omics, images, text, prior-knowledge, and real-world evidence.

• Lead interdisciplinary and cross-functional teams, including biologists, protein engineers, data scientists, and other stakeholders.

• Lead and contribute to high-profile presentations and publications, ensuring effective communication of research findings.

About You

Qualifications:

• Ph.D. in a scientific field with relevant experience in industry or academia; or a master’s degree with 4+ years of relevant experience; or bachelor’s degree with 6+ years relevant experience.
• A degree in Systems Biology, Computational Biology, or related field (Computational Science, Statistics, or Applied Mathematics) with strong knowledge of biological systems is preferred.
• Proven experience in developing ML/AI models in academia or industry using Python libraries such as PyTorch, TensorFlow, and JAX.

• Familiarity with learning from high-content perturbation data, such as transcriptomic or imaging readouts.

• Interest in addressing challenges in predicting the potential of combinatorial perturbation for drug discovery leveraging single-cell foundation models and lab-in-the-loop approaches.

• Record of innovation and impact, demonstrated through publications and patents.

  Strong communication, organizational, interpersonal, and teamwork skills, with a successful history of collaboration across analytical disciplines.

Why Choose Us:

• Bring the miracles of science to life alongside a supportive, future-focused team. 

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 

• Exposure to cutting-edge technologies and research methodologies. 

• Networking opportunities within Sanofi and the broader biotech community. 

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discovery Extraordinary.

Werde Teil von Sanofi und starte mit uns in eine neue Ära der Wissenschaft – wo dein persönliches Wachstum genauso wegweisend ist wie unsere Arbeit. Wir investieren in dich, damit du weiterkommst, schneller denkst und Dinge möglich machst, die vorher undenkbar waren. Du wirst Grenzen verschieben, Gewohntes hinterfragen und smarte Lösungen entwickeln, die direkt bei den Menschen ankommen, für die wir da sind. Bereit, die Wunder der Wissenschaft zu jagen und Leben zu verbessern? Dann lass uns gemeinsam Großes bewegen – und das Außergewöhnliche entdecken.

Bei Sanofi stehen allen die gleichen Chancen offen – unabhängig von Herkunft, Hautfarbe, Religion, Geschlecht, Nationalität, sexueller Orientierung, Alter, Staatsangehörigkeit, Familienstand, Behinderung, Geschlechtsidentität, Veteranenstatus oder anderen gesetzlich geschützten Merkmalen.