R&D
Where your curiosity drives the
miracles of
science

Job Title: Fall 2026 Co-Op - Process Chemistry

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Position Overview:

The Process Chemistry team, part of Sanofi's CMC Synthetics organization, is responsible for putting in place the synthetic route, optimization and process design for the commercial manufacturing processes for drug substances undergoing clinical development. Our team strongly believes that innovation is an important driver to reach success. We focus a large part of our activity on developing new synthetic routes, new concepts, and technologies to provide drug substances in a more efficient, more affordable, environmentally benign and intrinsically safe way.

We are seeking an undergraduate or graduate chemistry major to execute route scouting and process development for drug substances undergoing clinical development for approximately 6 months; the successful candidate will further develop synthetic organic chemistry skills in the lab, develop analytical and instrument techniques, learn process chemistry, and gain further understanding of the drug development process by participating in an industrial process chemistry group.

Main Responsibilities:

• Contribute to the design and optimization of novel and efficient synthetic pathways for drug substances undergoing clinical development to demonstrate synthetic viability

• Use all imaginable chemistry tools and methods to develop and optimize commercial process for selected drug substance route (photochemistry, biocatalysis, flow chemistry, electrochemistry, on-line analysis/PAT, high-throughput experimentation, structural analysis, computational chemistry, AI/ML and predictive tools, etc.)

• Design, plan and execute experimental plans to optimize reaction, purification and isolation unit operations, guided by technical risk assessments, to deliver safe, efficient, robust and scalable drug substance manufacturing processes that perform reliably at intended scale in batch or continuous format

• Learn to apply green chemistry principles to our R&D programs to develop sustainable manufacturing routes

• Develop/apply analytical techniques for structural characterization and interpretation (NMR and LCMS)

• Perform data analysis such as interpreting experimental results and designing next steps in collaboration with multiple mentors

• Maintain electronic laboratory notebooks according to SOP, provide detailed experimental procedures of laboratory work

• Communicate and interact with other staff/team members in a professional and courteous manner

• Operate in the lab in a safe and efficient manner according to HSE guidelines and adhere to all mandatory company compliance requirements

About You

Basic Qualifications:

• Currently enrolled and pursuing a master's or doctoral degree in Organic Chemistry at an accredited college or university

• Must be enrolled in school the semester following your internship/co-op with Sanofi

• Must be able to relocate to the office location and work 40 h/week, Monday-Friday for the full duration of the co-op/internship

• Must be permanently authorized to work in the U.S. and not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future. Students currently on CPT, OPT, or STEM OPT usually require future sponsorship for long term employment and do not meet the requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship

Preferred Qualifications:

• Chemistry coursework and lab coursework completed

• Experience in the use of various analytical instruments (e.g., NMR, LCMS) to interpret analytical data and fully characterize novel organic compounds

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Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com