
General Medicines
Where bold ideas and groundbreaking science shape
the future
of care
Medical Head Established and Legacy Portfolio Products, UKIE
At a glance
With us, you’ll break new ground across a growing and diverse portfolio – from established medicines that millions rely on to pioneering breakthroughs in immunology and chronic disease care. Imagine the scale: your work will help deliver treatments to people around the world who live with diabetes, cardiovascular disease, and complications arising from transplant.
Fueled by groundbreaking advances in technology, we are accelerating innovation and expanding access faster than ever. If you’re ready to push boundaries, embrace the power of AI and digital tools, and shape the future of healthcare, this is where your ambition meets impact.
Medical Head Established and Legacy Portfolio Products
Location: Reading, UK
Hybrid Working: 3 days per week in the office
About the job
The UK & Ireland Medical Team at Sanofi is a high-performing team of medical leaders who are a trusted source of scientific and Medical information and shared insights. The Established Products (EP) Franchise is a key part of Sanofi's General Medicines division. Our mission is to effectively support General Medicines' 2030 ambition with world-class management of a mature product portfolio addressing unmet needs in chronic diseases and delivering high profitability while maintaining a strong commitment to patients and corporate social responsibility.
As the Medical Head for Established and Portfolio Products, you will provide comprehensive medical leadership across two distinct but interconnected portfolios: actively promoted established brands in diabetes and cardiovascular that continue to deliver significant value through focused commercial and medical strategies, and legacy portfolio products that require expert medical stewardship, with particular emphasis on products requiring specialised regulatory attention such as valproate.
Main Responsibilities:
Strategic agility
Drive medical excellence and innovation for promoted brands to maintain their competitive position and unlock new value opportunities
Leverage digital/AI and Hubs capabilities to support medical activities
Drive strategic evolution of EP medical strategy to align with market dynamics and team transformation, specifically managing the transition from hero-hub-pureplay to primarily pureplay model while maintaining medical excellence
Ensure robust medical governance and lifecycle management for portfolio products, especially those with complex regulatory requirements like valproate
Balance resource allocation between actively promoted products and essential legacy brands
Provide differentiated medical leadership approaches based on product status while maintaining consistent high standards of patient care and safety
Serve as the primary medical expert for both actively promoted established brands and mature portfolio products, providing tailored strategic medical direction for each category
About you
Basic Qualifications:
Doctorate level education: MD or equivalent Medical degree or PharmD preferred
‘significant experience in Medical Affairs, ideally with relevant diabetes/endocrinology experience
Ability to travel up to 20-30% of the time
Thorough understanding of pharmaceutical industry regulations and codes
Proven experience in regulatory interactions and risk management programs
Skills & Competencies:
Strong business acumen with focus on balancing commercial opportunities for promoted products while ensuring appropriate medical governance of portfolio brands
Proven ability to lead change and drive medical excellence in established products
Deep understanding of benefit-risk management and regulatory requirements for mature products
Excellence in stakeholder management across multiple channels and therapeutic areas
Strong strategic thinking and decision-making capabilities in complex medical-regulatory environments
Proven ability to manage multiple priorities across diverse product portfolios
This role represents an exciting opportunity to shape the future of Established Products at Sanofi, combining strategic medical leadership of actively promoted brands with expert stewardship of our essential portfolio products. The successful candidate will drive medical excellence across multiple therapeutic areas while ensuring robust governance of products requiring specialized regulatory oversight. As the medical authority for established products, you will play a crucial role in maximizing the value of our legacy brands while ensuring their continued safe and effective use for patients worldwide. This unique position offers the opportunity to leverage deep medical expertise across diverse therapeutic areas, shape risk management strategies, and drive evidence-based decision-making in the evolving landscape of established medicine
Pursue progress, discover extraordinary
Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
Watch our ALL IN videoand check out our Diversity Equity and Inclusion actions at sanofi.com
nullPursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
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Why work with us
- Do the never done before. We push the boundaries of what’s possible: expanding access, accelerating innovation, and finding new ways to improve everyday health for millions.
- Drive the transformation. We’re leading the shift to AI-powered healthcare, using digital tools to reinvent how medicines are developed, manufactured, and delivered worldwide.
- Deliver at scale. Our reach is unmatched—we bring trusted treatments to millions worldwide, ensuring broad access and real-world impact at every stage of care.
- Make an impact that matters. From tackling global health challenges to advancing sustainable, inclusive healthcare, everything we do is driven by purpose.
Who ignites your potential?
For Sam, it was her mom—teaching her to listen, push boundaries, and put patients first. At Sanofi, we know your inspiration drives your impact. Bring your passion, and together, we’ll chase the miracles of science.

"Each disease, each country, each person brings opportunities that challenge us to push the boundaries, to think of better ways to look at healthcare and pioneer new possibilities."

Olivier Charmeil
Executive Vice President, General Medicines
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