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Job title:Principal Scientist I, Biological Insights & Analytics, Immunology, Neurology, & Oncology

• Location: Vitry-sur-Seine

About the job

As Principal Scientist I within our Biological Insights & Integration team, you'll drive precision medicine strategies and lead cross-functional projects that advance Sanofi's mission as a leading immunoscience company. Ready to get started?

Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions. This role reports into the Biological Insights & Integration (BII) cluster within the Target, Disease and Systems Biology (TDSB) function at Sanofi research, serving as a key player in planning, interpretation, and execution of precision medicine activities across multiple therapeutic areas.

About Sanofi:

We're a R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main responsibilities:

• Contribute deep scientific expertise in immunology & inflammation, neurological diseases, and/or immuno-oncology to advance research programs across multiple stages of development

• Formulate hypotheses and interpret results from integrated analysis of molecular, clinical,pathological, and in silico data to develop patient stratification approaches

• Analyze multi-modal profiling datasets from patients with immune, oncology, and/or neurodegenerative diseases using R and/or Python or similar programming languages

• Lead cross-functional projects involving TDSB, research therapeutic areas, Early Development & Translational Medicine and Digital functions

• Collaborate with external stakeholders through vendor relationships and consortia participation to execute strategic initiatives

• Coordinate programs from research into early clinical development (forward-translation) and vice versa (back-translation)

• Develop approaches to explore drug mechanisms-of-action, therapeutic strategies, and responses using AI/ML tools

• Represent Sanofi at conferences and scientific gatherings, building strong partnerships across the organization and with external KOLs

About you

Education and Experience:

• PhD in life sciences, PharmD and/or MD with 4+ years or MS with 7+ years of experience in the pharmaceutical industry or equivalent. ‘Bilingual’ scientists with deep biological expertise and proficiency in bioinformatics and multiOmic data analysis would be at an advantage

Soft and technical skills:

• Advanced understanding of diseases with clear vision about precision medicine approaches in drug development

• Deep understanding of unmet medical needs in Immune-Inflammatory and neurological conditions and/or complex immune diseases

• Strong publication record and advanced understanding of genetic and genomics data analytics

• Outstanding written and oral communication skills in English required; French language skills viewed favourably

• Ability to function in diverse teams and lead cross-functional projects in a matrix environment

Languages:

• English (fluent). French is a plus

Why choose us?

• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science

• Help improve the lives of millions of people globally by making drug development quicker and more effective

• Enjoy opportunities to collaborate beyond your area of expertise, working with diverse teams across science, clinical, and digital fields

• Accelerate your professional development with structured career paths designed for both scientific and leadership advancement

• Join a workplace where diversity, equity, and inclusion are at the core, with Employee Resource Groups and leadership programs that celebrate every voice

PursueProgress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together. 

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

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