Associate Scientist - Computer-Aided Drug Discovery (CADD), Integrated Drug Discovery

Job Title: Associate Scientist - Computer-Aided Drug Discovery (CADD), Integrated Drug Discovery

Location: Cambridge, MA,

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate Progress. 

A computational chemist, with a strong track record of computational modeling research.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

• Provide computational chemistry support, including cheminformatics, structure and ligand-based hit identification and lead optimization.

• Perform in-depth analysis of project data, such as HTS results, biochemical assay results, biophysical data, and propose new studies and experiments.

• Develop and apply predictive models to support medicinal chemistry efforts in the design and prioritization of novel bioactive compounds based on emerging data.

• Use knowledge and experience to proactively collaborate with other team members to design target compounds which address challenges and/or test a hypothesis.

• Understand and articulate the scientific rationale of the project to other scientists.

• Provide formal and informal mentoring of computational tools within project team and medicinal chemists in the department.

• Conduct and analyze patent searches, assess the patentability of designed compounds, assist with filing of patent applications.

• Actively participate in project team meetings, communicate in a clear and precise manner, raise questions, and contribute to the project.

• Work closely with medicinal chemistry & structural biology scientists with shared ownership and accountability of project.

• Communicate and interact with staff members in a professional and courteous manner.

• Champion new modeling techniques and participate in software evaluation and recommendation.

• Collaborate with data scientist to implement predictive models/tools within informatics platform.

• Adapt to changes and challenges in a productive and professional manner.

• Conduct work according to HSE guidelines and adhere to all mandatory company compliance requirements.

• Act as an ambassador for the department and company, attend appropriate scientific meetings to increase knowledge and stay current with journal and patent literature.

About You

Requirements & Qualifications

• Master’s degree in physical organic chemistry, biophysics, medicinal chemistry or related field plus 3 years of related experience.

• Recognized as a technical expert with growing scientific and subject matter expertise and innovative contributions.

• Proficient in the use of modeling techniques (machine learning, and absolute binding free energy calculations, metadynamics and Monte Carlo simulations) and capable of developing and automating workflows.

• Demonstrated skills in developing and implementing AI-based algorithm and method for property predictions.

• Emerging track record as a contributor providing quality science that forms the basis for publications, presentations and patents and involvement in professional society.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA 
#LI-SA    

#LI-Onsite
#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.