Indication Lead Frexalimab MS

Job Title: Indication Lead Frexalimab MS

Location: Cambridge, MA

About the Job

Frexalimab is one of Sanofi’s top 12 priority assets, and 1 of 3 with a communicated ambition of €5B+ across its indications. The MS indications are forecasted to contribute €2B+ at peak sales with current forecasted first launch date in Q4 2028.

Frexalimab (SAR441344) is a potentially first-in-class anti-CD40L antibody that blocks the costimulatory CD40/CD40L pathway which is important for activation and function of adaptive (T and B cells) and innate (macrophages/microglia and dendritic cells) immunity. Through this unique upstream mechanism of action, frexalimab has the potential to address both acute and chronic neuroinflammation in MS, without causing lymphocyte depletion. Frexalimab is currently being studied in RRMS, SPMS, T1D and SLE.

The role’s primary responsibility will be to lead the development and execution of innovative brand marketing strategies and tactics that will differentiate Frexalimab in MS, to create a best-in-class experience for all stakeholders.  This position reports to the GBL Frexalimab and leads the development and execution of the MS strategy for Frexalimab. The Global Indication Lead Frexalimab MS will work with the Global Brand Lead to establish and run the Frexalimab MS GBT, partnering with cross functional stakeholders and country partners.

In the future, the Indication lead Frexalimab MS will lead a team of marketing professionals. This role has the potential to evolve to an L5 level in the future, as the asset evolves and the team develops.

We are an innovative global healthcare company, committed to transforming the lives of people with immune challenges, rare diseases and blood disorders, cancers, and neurological disorders. From R&D to sales, our talented teams work together, revolutionizing treatment, continually improving products, understanding unmet needs, and connecting communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

Main Responsibilities:

• Responsible for the successful development and execution of the global Frexalimab MS marketing strategy, to support ongoing worldwide country launches

• Co-leadership of the Frexalimab MS Global Brand Team partnering across key functions and in partnership with launch countries, leading key aspects of Global launch plan development and ensuring alignment of local launch plans

• Develop global positioning, branding guidelines, core messages and campaign execution tools (including digital/multichannel)

• Lead the annual Frexalimab MS Global Brand plan process

• Lead Frexalimab business case guidance document development & process to assess business cases with markets

• Differentiate from competition and support development of high-impact, global patient-focused strategy and tactical initiatives to drive a best-in-class brand experience for all frexalimab MS customers

• Solicit ongoing input from priority countries/regions, and provide clear direction on local country frexalimab MS implementation

• Engage external MS stakeholders to ensure strategy includes customer insights

• Co-develop the Frexalimab MS brand strategy in partnership with cross-functional colleagues, to ensure aligned objectives and tactical implementation across the broader team, including alignment & partnership with tolebrutinib team

• Monitor and support Frexalimab MS country launch readiness and launch performance

• Work in partnership with the GBL Frexalimab to ensure consistency, where required, for select brand elements across all Frexalimab indications (e.g. communication elements)

• Manage annual budgets, ensuring strategic allocation of funds and monthly tracking

• Lead the selection of the agency of record and lead ongoing management of the advertising agency partner and other vendors to ensure execution towards objectives

• In future- Attract, develop, and retain talent to foster a best in class global Frexaliamb marketing team

About You

Experience Qualifications:

• Bachelor's degree in life sciences, marketing or business required

• Minimum of 15 years’ experience in product/brand management, sales management and/or strategic marketing

• Experience in US & international marketing (non-U.S.) within a complex, global commercial pharmaceutical or biotechnology organization

• Strong Global HCP marketing background with expertise in execution across all channels

• In-depth understanding of the MS market, and external expert network

• Product launch experience in specialty care/biologics

• Experience collaborating with cross-functional groups, made up of the following: Marketing, Sales, R&D, Medical Affairs, Market Research, Finance, Forecasting, Launch Excellence etc.

• Comfortable leading in a matrix environment without direct authority

• Line management/team leadership experience 

• Proven ability to work across different countries and different cultures

• Experience managing an advertising agency and related budgets

Preferred Qualifications

• Second degree, e.g. MBA, PhD, M.Sc.

Professional Skills

• Passionate, confident and comfortable in team environment

• Excellent interpersonal, and communication skills.

• Demonstrated analytical skills, strategic thinking and prioritization capacity

• Ability to process complex information, then simplify and communicate it effectively with others

• Demonstrated ability to understand and anticipate customer needs (internal and/or external)

• Proven ability to cooperate transversally and lead in an ambiguous environment across different functions

• Strong organizational and project management capabilities

Behavioral competencies

• Performance orientation and ability to work and deliver along agreed timelines

• High level of Interpersonal and communication skills

• Self-starter, Initiative & proactivity- Strong internal drive

• Team oriented

• Readiness to travel (up to 35% of time)

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.