Skip to main content
Research and Development

R&D
Where your curiosity drives the
miracles of
science

Clinical Digital & AI Acceleration Innovation Manager

Cambridge, Massachusetts
Morristown, New Jersey
Salary Range   USD 178,500.00 - 257,833.33
Apply now

At a glance

Bring your curiosity to a team where deep immunoscience meets cutting-edge innovation. Across oncology, rare diseases, neurology, and vaccines, you’ll work at the intersection of lab science and AI-powered discovery — all while collaborating across boundaries to turn breakthrough ideas into real-world impact. Whether you want to deepen your scientific expertise or grow as a leader, you’ll find the opportunity here.

Job Title:Clinical Digital Acceleration Innovation Manager

Location:  Cambridge, MA

About the Job

Join the engine of Sanofi’s mission — where deepimmunosciencemeets bold, AI-powered research. In R&D,you’lldrive breakthroughs that could turn the impossible into possible for millions.

Sanofi is a leading bio-pharmaceutical company committed to advancing healthcare through groundbreaking research and development. Our dedicated function – Clinical Sciences & Operations (CSO) - plays a vital role in ensuring accurate and compliant clinical trial submissions and project operations, contributing to the approval of innovative therapies that transform patients' lives.


Within CSO, the Modernization & Performance Office (MPO) acts as a key enabler of transformation and modernization, driving strategic initiatives that enhance efficiency, digital innovation, and operational excellence across the function. As we continue our business transformation and drive excellence and innovation in our processes, we are seeking an exceptional professional to join us as Digital Acceleration & Innovation Lead.

The Clinical Digital & AI Acceleration innovation Manager is a CSO-wide, function-level leadership role reporting to the Head of Clinical Digital & AI Acceleration, with explicit accountability for shaping, steering, and realizing the value of CSO’s digital and AI transformation agenda across Sanofi’s Clinical Sciences & Operations (CSO).

The role operates as a strategic authority rather than a delivery contributor, responsible for orchestrating global-scale digital and AI transformation across clinical development, with decision rights on portfolio prioritization, investment trade-offs, resource allocation, and execution strategies within the transformation portfolio. The incumbent directly influences CSO operating model evolution, ensuring that digital and AI initiatives fundamentally reshape how clinical trials are designed, executed, and governed globally, with measurable business, quality, and patient impact.

The position combines strong digital and AI domains with function-level business and transformation leadership, requiring the ability to produce decision-grade insights for CSO leadership, translate complex technology and regulatory constraints into strategic value hypotheses, and steer outcomes across highly matrixed, regulated environments. The role also leverages competitive and technology intelligence to proactively shape CSO strategic choices.

If you are a visionary leader with a passion for transforming clinical operations processes and driving innovation in clinical research, we encourage you to apply for this exciting opportunity. Join our team and contribute to our mission of improving patient outcomes through cutting-edge therapies.

About Sanofi

We’rean R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities

Portfolio Management

  • Co-own and lead CSO Digital & AI transformation initiatives at function level, ensuring alignment with CSO strategy, business priorities, and value realization commitments.

  • Exercise decision authority on initiatives prioritization, sequencing, and trade-offs to maximize CSO-wide value and time-to-impact.

  • Align strategically and operationally CSO’s flagship transformation initiatives (e.g., ACT4Patients & eDEV) to ensure coherence, integration, and early realization of business outcomes

  • Continuously challenge and recalibrate the transformation roadmap based on business performance data, field feedback, and competitive intelligence

  • Ensure global visibility and governance alignment across all internal and external digital innovation initiatives (Clinical Innovation, external forums, partnerships, etc.)

  • Evolve the Initiative Portfolio Management Office (iPMO) as a CSO governance and decision-enablement mechanism, not a procedural framework

  • Define, institutionalize, and enforce governance standards (business cases, ROI logic, value tracking, scale-up criteria, stop/pivot decisions)

  • Hold transformation teams accountable for outcome-based delivery and value realization, beyond milestone completion

Transformation Projects Leadership and Engagement management

  • Lead and sponsor selected high-impact, multi-million-euro, clinical-development critical transformation programs with Digital and/or AI components

  • Accountable for end-to-end outcomes, including strategic alignment, financial performance, adoption, scale-up, and sustained value delivery

  • Direct and validate: Competitive and technology intelligence to inform strategic positioning, function-level business needs and value hypotheses, prioritization of business-driven requirements shaping product and roadmap decisions & gaps analysis against existing solutions and operating models

  • Provide strategic direction on vendor models, sourcing strategies, and contractual frameworks in alignment with CSO transformation priorities

  • Oversee financial planning, investment phasing, and resource allocation to optimize enterprise ROI

  • Influence CSO-wide positioning and integration of strategic platforms (e.g., NEXUS, TrialPulse, Concierge)

  • Ensure successful enterprise deployment and scale-up, tracking realized benefits beyond pilot or proof-of-concept stages

  • Own risk, dependency, and performance steering, escalating and arbitrating at CSO leadership level as required

Digital & AI Acceleration Capability Building

  • Define and own CSO-wide frameworks for measuring ROI, business impact, adoption, and maturity of digital, data, and AI initiatives

  • Provide portfolio-level, decision-grade visibility on solution interdependencies, capability impacts, and end-to-end process transformation

  • Institutionalize lessons learned and drive continuous improvement across the CSO transformation ecosystem

  • Continuously scan and interpret external technology, AI, and regulatory trends, translating them into actionable CSO transformation opportunities

Stakeholder Engagement & Collaboration

  • Engage, influence, and challenge CSO senior leadership and executive stakeholders as a trusted transformation and governance partner

  • Represent portfolio status, risks, and value realization in executive governance forums, providing clear recommendations and decision options

  • Co-lead CSO-level digital and AI strategy forums, shaping leadership understanding and adoption of innovation

  • Build and maintain enterprise partnerships beyond CSO (TMU, GRA, PV, Digital, etc.) to accelerate transformation at scale

  • Act as an enterprise integrator between business, technology, and data teams, ensuring alignment and accountability

About You

Experience:

  • Minimum 8 years of experience in enterprise digital transformation, portfolio leadership, or strategic program governance

  • Proven track record leading large-scale digital, data, or AI-enabled transformation in complex, regulated environments

  • Strong experience in BVA modeling, ROI tracking, and benefit realization

  • Proven ability to influence executive decisions and steer outcomes without direct hierarchical authority

  • Understanding of clinical development, with enterprise exposure to GCP, ICH-GCP, and operational quality frameworks

Leadership and Behavioral Competencies:

  • Function-level strategic and systems thinker, able to connect initiatives to value chains and operating-model shifts

  • Strong analytical rigor combined with executive judgment and decisiveness

  • Credible, confident presence at senior leadership and executive level

  • Outcome- and value-oriented mindset with clear ownership and accountability

  • Excellent cross-functional, cross-cultural leadership and orchestration skills

Education:

  • Master's degree or PhD in a relevant field such as (but not limited to): Computer Science, Data Science/Analytics, Engineering (with focus on AI/ML). MBA will be a plus.

Languages

  • Fluent in English

Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whetherit’sthrough a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Takegood careof yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare,preventionand wellness programs and at least14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA 

#LI-SA

#LI-Onsite

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.

Apply now
Illustration of map pins on globe

Find out more about this location

Scientist in a lab coat examines a sample under UV light in a modern laboratory environment.

Why work with us

  • Expand your horizons. Grow through curiosity, with support to move, learn, and lead in a culture that champions mentorship, mobility, and bold development.

  • Accelerate results with technology. Harness the power of AI and automation to push scientific boundaries and reimagine what's possible in drug discovery.

  • Impact through inclusive innovation. Help deliver better science and fairer outcomes by driving inclusive research that reaches more people, in more meaningful ways.

  • Turn patient needs into breakthrough science. Drive scientific breakthroughs that start with patient needs – and end in treatments that change lives.

Meet Nils Libert, Associate Scientist

Meet Nils Libert, an Associate Scientist in Belgium, where he plays a key role in advancing groundbreaking research. Learn how his work helps drive innovation, uncover new scientific possibilities, and contribute to life-changing treatments that impact patients around the world.

icon of a speech bubble
"At Sanofi, we are building an R&D engine powered by the best science, digital innovation, and a commitment to transforming the lives of patients around the world."

Houman Ashrafian

EVP & Head of R&D

Discover more

Scientist in a Sanofi lab

Our R&D focus areas

Discover how we're reshaping the future of medicine through immunoscience – unlocking bold, cross-disease breakthroughs that were unimaginable just a decade ago.

Learn more

Close-up of lab equipment in use

Meet Sanofians in the labs

Step inside our labs and hear from the scientists turning cutting-edge science into real-world impact – driven by curiosity, collaboration, and purpose.

Voices from the labs

Join our
talent community

What could we achieve together? Every Sanofian works on projects that truly make a difference to people’s lives.

Sign up today and discover our latest opportunities as soon as they’re available.