
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
EM&S Large Molecules GenMed Operations Head
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
EM&S Large Molecules GenMed Operations Head
Location: Framingham, MA /Cambridge, MA / Morristown, NJ / Northborough, MA
About the job
We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.
Reporting to the Head of External Site Team Large Molecules GenMed,is accountable tomanage and transform the Operations role within EM&S LM GenMed and leads Operations personnel.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Main responsibilities:
The Head of Large Molecules GenMed Operations will workin partnership with The Head of the External Site Team, the External Manufacturing Product Teams (EMPT) heads and the other functional heads (Quality, Supply Chain, etc) and in alignment with all EM&S business partners
Supports on time and in full delivery of products for CMOs within External Site Team, accountable for reporting of GenMed LM & EM&S Operations KPIs.
Lead the team monitoring the operational execution of the contracts, serving as primary focal point for daily operations and ensuring routine oversight at CMOs during manufacturing campaign.
Drives continuous improvement in internal and CMOs performance areas of Safety, Quality, Cost & Delivery.
Contribute to new flows and specifications implementation at CMOs.
All aspects of people management for EST Operations personnel and accountable for financial resource planning within budget, including generation and maintenance of labor model.
Supporting Sanofi's DE&I initiatives. Develops and maintains a positive culture to create the right environment for highly productive teams in a psychologically safe environment.
Advisor on the management of product/CMOs from an operational and financial perspective, contract topics and technical support. Ensure all EM&S operational related aspects of tech transfers and commercialization into new CMO's are effective.
Drives Standardization & Simplification initiatives working with functional heads and the Center of Excellence Technology, SMS, and Digital team.
Work with EMPT & CMO Business Operations Team to standardize contracts. Contribute to the introduction of new digital tools, (e.g., Power BI and Plai).
Work with EST and Procurement on implementation of cost saving initiatives.
Support problem resolution between Ops personnel & both internal and external business partners.
Support problem resolution between Ops personnel & both internal and external business partners.
Support problem resolution between Ops personnel & both internal and external business partners.
About you
Bachelor's degree with 10 years' experience or master's degree with 8 years' experience in pharmaceutical/biotech operations.
Leadership experience in operational roles such as Site Manager, Senior Leadership Team member, or Production Manager.
Strong knowledge of industrial business processes, E2E product strategy, and performance management.
Experience with cross-site collaboration and understanding of biotech/pharmaceutical manufacturing technologies.
Analytical skills with ability to set and monitor KPIs, plus basic understanding of data management and digital tools.
Project management expertise with demonstrated ability to drive operational excellence initiatives.
Collaborative leadership style with ability to influence across organizational boundaries
Languages: Fluent English, French as a plus
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants
will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic
partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability
for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or
any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Sanofi US endeavors to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please click here.
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
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Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
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