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Vaccines

Vaccines
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extraordinary minds
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half a billion people

Senior Lead Clinical Modeler-Vaccines

Cambridge, Massachusetts
Morristown, New Jersey
Swiftwater, Pennsylvania
Salary Range   USD 147,000.00 - 212,333.33
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Who we are

Every day, 2.5 million Sanofi vaccine doses reach patients worldwide - powered by bold ideas, cutting-edge science, and passionate people like you. Across every stage — from discovery to delivery — Sanofians are shaping the future of vaccines. In global R&D hubs, exceptional offices, and state-of-the-art manufacturing sites, we’re reimagining what’s possible. But science alone isn’t enough — it’s the extraordinary minds behind it that truly make the difference.

Job Title:  Senior Lead Clinical Modeler-Vaccines

Location: Cambridge, MA Morristown, NJ Swiftwater, PA

About the Job

The Global Biostatistical Sciences department at Sanofi Vaccines is seeking to hire a highly talented mathematical, statistical and computational modeling scientist to support its Vaccines R&D portfolio.  The Global Biostatistical Sciences group is part of the Vaccines R&D organization.  Modeling & simulation brings unique opportunities to inform decision making and streamline the various steps of vaccines discovery and development.

Are you ready to shape the future of vaccines development? Sanofi is committed speeding up vaccines discovery and development to continuously improve public health and patients’ life. Your talent could be of deep value in helping our project teams accelerate progress through modelling. Join our team as Senior Lead Clinical Modeler, and you’ll actively contribute shaping the future of our vaccines portfolio.

We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

Main Responsibilities:

  • Develop complex quantitative vaccine models (e.g.: virtual individuals immune response in different scenarios, correlate of protections, disease epidemiology,…) in close collaboration with multidisciplinary teams to inform and optimize vaccine development.

  • Develop and run in-silico clinical trials in virtual individuals to de-risk, optimize, and accelerate vaccines development.  

  • Predict the future through simulations – e.g., Lead the use of models to predict the future trajectory of disease during vaccine trials, including the location, number of cases, peak infections, and duration of transmission and infection in the populations to be studied.

  • Lead the continuous update and refinement of models based on new data and insights from research and real-world results

  • Assessment and prioritization of modeling strategic contribution to ensure quality and timely impact of modeling and simulation work packages.

  • Clear communication of modeling results (e.g., Prepare reports and presentations to communicate model findings to stakeholders, including decision makers.).

  • Bring the implementation of scientific and technological innovations in the area of disease and vaccines impact modeling.

About You

Qualifications

  • Ph.D. degree in a quantitative scientific field such as epidemiology, biostatistics, immunology, computational systems biology, or applied mathematics
  • 7+ years’ experience in pharmaceutical clinical research with at least 3 years modelling experience
  • Demonstrated evidence of comprehensive understanding of mathematical modeling techniques, SEIR models, differential equations, compartmental models, and statistical analysis, ideally evidenced by relevant publications
  • Established knowledge of infectious disease epidemiology, including disease transmission, natural history, and control measures. Ability to analyze longitudinal epidemiological data, estimate model parameters, and interpret model outputs
  • Demonstrated proficiency in programming languages (e.g., Python, R) for implementing models and in AI/ML
  • Demonstrate project management skills, customer orientation and influencing skills
  • Build and maintain effective strategic working relationships with internal and external partners to meet business needs.
  • Identify, develop and implement novel methodologies and invest in expanding expertise across clinical, regulatory, and commercial domains
  • Demonstrate ability to stay current with the latest research and adapt to new technologies and methodologies
  • Ability to work independently and collaborate effectively in interdisciplinary teams
  • Ability to effectively communicate model results and recommendations to statistical, clinical, and senior management colleagues

Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Sanofi US endeavors to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please click here.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

What does it take to protect the world from disease?

For over a century, we’ve been pioneering breakthroughs that help protect millions from diseases like polio, influenza, RSV, and more. And we’re not stopping there.

Powered by groundbreaking technologies - mRNA platforms, recombinant proteins, and AI-driven insights - we’re pushing the boundaries of science.

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"I’m immensely proud of the pace of our innovation – the urgency by which our teams are working to transform the practice of medicine."

Thomas Triomphe

Executive Vice President, Vaccines

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Sanofi’s mRNA Center of Excellence

Step into the future of healthcare with Sanofi’s mRNA Center of Excellence. Discover how a global team is transforming medicine with cutting-edge mRNA technology – and explore the skills, inspirations, and breakthroughs driving this revolution. Ready to shape the future?

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About Sanofi Vaccines

Explore our commitment to protecting global health through the power of vaccines. We’re building healthier communities with innovative solutions that save millions of lives each year. Dive into the future of vaccines, discover the diseases we’re tackling, and learn why vaccination is critical at every stage of life.

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