
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
Specialty Care GBU Global Demand and Portfolio Lead
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
Job Title: Specialty Care GBU Global Demand and Portfolio Lead
Location: Cambridge, MA
About the Job
We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Sanofi aims to become the world’s leading immunology company. Our M&S mission is clear: we need to launch an unprecedented number of new products, and become the industry benchmark, by building a modern, fully integrated and digitized M&S network connected to R&D and commercial.
The Demand & Portfolio Lead is accountable for the consolidation and the risk assessment (de-risking or buffering) of the demand in collaboration with Supply Chain Product leaders. This person is accountable for the product life cycle management process in the IBP horizon (Product Management Review – PMR Process). Responsibilities require ensuring End-to-End collaboration across Supply chain, Finance, Commercial, Franchise, & Manufacturing & Supply.
Role reports to Specialty Care Global GBU Supply Chain Head of Integrated Business plan, Sales & Operational Excellence and Performance.
The Demand & Portfolio Lead is accountable for the consolidation and the risk assessment (de-risking or buffering) of the demand in collaboration with Supply Chain Product leaders.
They are accountable for the product life cycle management process in the IBP horizon.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Main Responsibilities:
Accountable of the consolidation and the risk assessment (de-risking or buffering) of the demand in collaboration with Supply Chain Product leaders.
Builds standard & harmonized Demand Reviews process and slide-decks across Therapeutic area to simplify & optimize IBP process.
Coordinates with Product Leads Global unconstrained demand forecast on 36months horizon, reviews main R&O ant GBU level and aligns on demand escalation topics to MBR.
Identifies main variations & collaborate with SC Product Leaders in understanding root causes and proposing action plans to mitigate Demand variations.
Runs demand risk assessment for High volatile brands/markets in collaboration with SC Product Leaders/ TA Head, proposing demand de-risking or demand buffering to drive demand stability
Runs demand scenario planning with Finance to identify breakeven points of demand opportunities to help decision making.
Ensures consistency of 0-3y Tactical horizon with 4-10y Strat Plan Franchises assumptions
Reviews current commercial product portfolio (including product rationalization), New product pipeline and activities for market products which has impact on demand, Supply and Financial Plans.
Identifies demand and supply impacts through product portfolio changes. Share an overview of portfolio evolution, complexity reduction, market trends & innovations.
Leads the preparation and animation of the Product Management Review (PMR)
Drives timely readiness of master data in support of new launches
Drive yearly SKU portfolio review to identify candidates for discontinuation (low sales value, dilutive margin, low batch size)
Leads the SKU portfolio rationalization program in collaboration with Franchises, TA Lead, Regulatory Affairs, Finance & Com ops
About You
Skills/Expertise/Experience:
Experience in developing strategies and budgeting long-range planning
Solid knowledge of IBP process
Experience with performance and capability in enabling and driving change
Strong communication and influencing skills, including stakeholder management with senior leadership
Advanced knowledge of Demand Forecast and Supply Management
Experience modelling scenarios with multiple variables incorporating identification of key drivers, risks, financials, and sensitivity analysis.
Understanding of business requirements of GBU, especially in key markets
Ability to operate in complex matrix environments across multiple teams and geographies
Able to easily cooperate transversally and to connect teams
Strategic thinking and ability to capture the whole picture
Ability to reach consensus
Accountability, reliability and ability to work in transparency
Open minded and active listening
Ability to perform independently and in a collaborative environment.
Basic Qualifications
Minimum Four-Year Degree. *Preferred degree focusin Engineering, Business Administration or Supply Chain
Minimum 10 years relevant experience in the Pharmaceutical Industry in Supply Chain / Commercial Operations / Demand Management / Finance.
Experience in developing strategies and budgeting long-range planning
Advanced knowledge of Demand Forecast and Supply Management
Experience modelling scenarios with multiple variables incorporating identification of key drivers, risks, financials, and sensitivity analysis.
Preferred Qualifications
Degree in Engineering, Business Administration or Supply Chain preferred
Preference for an experience with an international organization with proven and demonstrated ability to influence on a transversal basis across multiple stakeholders.
Ability to operate in complex matrix environments across multiple teams and geographies
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
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Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

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Executive Vice President of Manufacturing and Supply
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