
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
EM&S External Site Team Head for Large Molecules GenMed
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
About the job
External Manufacturing and Supply (EM&S) Large Molecules GenMed organization manages all Contract Manufacturing Organizations (CMOs) across the GenMed Global Business Unit (GBU) that deliver Sanofi's large molecule products. We serve the GBU within Manufacturing & Supply with drug substance, drug products, and finished goods. Our organization strives towards three key priorities: (i) Ensure Supply, (ii) Deliver Financially, and (iii) Grow Talent. Beyond our core business operations, we are transforming the business by establishing strategic partnerships and implementing advanced technology for centralized CMO performance management.
Main responsibilities:
Lead the Large Molecules GenMed External Site Team, ensuring timely delivery of products from CMOs
Drive continuous improvement in Safety, Quality, Cost, Delivery & Involvement metrics
Develop and maintain strategic partnerships with external partners and internal stakeholders
Manage financial performance including budgets, cost savings, and P&L responsibilities
Oversee contract management and strategic planning initiatives
Lead risk management programs and ensure quality compliance
Participate in quality governance forums and oversee critical deviation approvals
Build and manage high-performing teams in an inclusive environment
Drive standardization of CMO management processes and procedures
Collaborate with cross-functional teams including Legal, Quality, Finance, and Regulatory
Ensure effective resource allocation and project prioritization
Support strategic portfolio management and lifecycle projects
About you
Experience: Demonstrated experience in operational roles, preferably as Site Manager or Senior Leadership Team member
Soft skills:
Strategic thinking with ability to shape vision
Strong leadership and team development capabilities
Excellence in relationship building and communication
Adaptability and comfort with ambiguity
Results-driven with proven execution skills
Technical skills:
Understanding of E2E product & industrial strategy
Knowledge of performance management and project management
Familiarity with biotech/pharmaceutical industry technologies
Strong analytical capabilities
Proficiency in KPI management and digital tools
Education:
Bachelor's degree with scientific background or equivalent
Master's degree preferred
Languages: Fluent in English; French is a plus
Additional Requirements:
Experience in industrial business processes
Understanding of data management and AI digital products
Cross-functional and cross-site networking experience
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
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Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
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