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Manufacturing and Supply

Manufacturing and Supply
Where the
miracles of
science
are made
a reality
for patients

Site Head of Opex & Smart Factory Head

Le Trait, France
Apply now

At a glance

Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.

Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail.

This job offer is accessible to all, regardless of gender.

Job title: Site Head of Opex & Smart Factory Head 

  • Location: Le Trait

About the job


As Site Head of Opex & Smart Factory Head within our Le Trait Senior Leadership Team, you’ll bring the site to the next level in terms of Performance & Innovation, in particular in the digital & IA fields. Ready to get started?


Join a global network that powers how Sanofi delivers — seamlessly, purposefully, and at scale. In Manufacturing & Supply, you’ll help reimagine how life-changing treatments reach people everywhere, faster. 
The job is located at Le Trait, Normandy, France. The site belongs to Dupixent Cluster – Specialty Care GBU within Sanofi M&S Network.


Le Trait site is a center of excellence for innovative injectable products: a modernized, digital & attractive factory at the heart of the Group Strategy as Leader in Immunology by Shifting our Safety (Towards 0 accident) and Quality Culture (100% batch RFT) , Shaping our future (state of the art processes & equipment, starting innovative products, paperless & powered by AI) & Enhancing the competitiveness of our products and their availability (Best in class PCT, Towards Top Q).

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main responsibilities:

  • Lead and execute the Site Performance Roadmap, driving strategic initiatives and performance breakthroughs
  • Spearhead digital transformation through Smart Factory solutions implementation, including AI and data analytics
  • Drive operational excellence through SMS 2.0 ecosystem deployment and continuous improvement initiatives
  • Manage site performance governance and KPIs across Quality, Delivery, Cost, and Innovation dimensions
  • Lead the development and execution of the Site Digital Roadmap
  • Build and develop a high-performing OpEx and Digital team
  • Oversee master data governance and analytical capabilities deployment

About you 


Experience:

  • Proven track record in driving performance improvement initiatives in manufacturing
  • Experience with smart manufacturing technologies and digital solutions implementation
  • Soft and technical skills: 
  • Strong leadership experience in operational excellence and digital transformation
  • Strong analytical and strategic thinking capabilities
  • Excellent stakeholder management and communication skills
  • Advanced project management expertise


Education:

  • Engineer or pharmacist or Master degree in sciences or equivalent


Languages:

  • Fluent in English; additional languages are a plus
  • French is a must

Why choose us?

  • Power industry-leading performance by leveraging digital, data, and AI-driven innovation – at speed and scale
  • Grow, thrive, and make an impact in a workplace that empowers you to bring your best self every day, with pride. Help deliver 30+ new product launches by 2030, ensuring patients get treatments faster than ever
  • Sustainability, leading the industry in low-carbon manufacturing and digital transformation

PursueProgress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

#LI-DNI 

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Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Apply now
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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

All-in on diversity

At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

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"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan

Executive Vice President of Manufacturing and Supply

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