
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
Integrated Manufacturing Execution System Engineer
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
About the Job
Sanofi Manufacturing and Supply organization is preparing its future through an ambitious program named Modulus. The Modulus Project is at the cornerstone of Sanofi strategy as it aims at creating a new manufacturing concept consisting of a new generation of evolutive multi-product facilities, modular, adaptable and agile, leveraging new disruptive technologies, to better address vaccine business challenges as well as Specialty Care Biologics products.
Main Accountabilities
· Configure, maintain, and update MES and DHS to support production needs effectively
· Support system implementation and upgrades
· Configure and optimize MES, Data Historian, and OT Connectivity systems
· Manage and maintain technical data, including equipment properties
· Troubleshoot and continuously improve IMS performance
· Lead MES-related projects for new products and production setups in APU
· Participate in global networks, contribute lessons learned to the network
· Participate in global initiatives when requested
· Responsible to understand current global design guidelines and application
· Provide SME support for deviation root cause analysis
· Lead implementation of MES scope for site CAPAs
Key roles (D,.A,.I)
· A: Advise on system configuration changes and updates to improve functionality
· A: Review and approve system configurations as per site needs
· A/I: Support data integrity and oversee data management practices
· A/I: Guide local project implementations to ensure MES integration
· I: Involved in system design and upgrade discussions, providing technical insights
· I: Implement improvements based on performance analysis
Expected Experience
· Strong experience in MES and Data Historian systems (Siemens OpCenter and Aspen IP.21)
· Experience of interfaces management between MES and manufacturing equipment
· Experience with Industry 4.0 technologies implementation
· Experience in troubleshooting and enhancing system performance
Expected Technical skills
· Results-Oriented
· People Leadership
· Influencing Others
· Automated Manufacturing Systems
· Project Management
· Connectivity Software
· GMP Compliance
· Pharmaceutical Manufacturing
nullPursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
Find out more about this location

Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
Discover more

Manufacturing & Supply Careers
Explore how Sanofi is transforming pharmaceutical manufacturing and supply chains with cutting-edge technology, digital innovation, and sustainable practices. Discover career opportunities where you can help deliver life-changing medicines efficiently and responsibly.

Accelerating Biopharma Innovation with McLaren Racing
What do Formula 1 and biopharma have in common? Speed, precision, and a drive for excellence. Discover how Sanofi is partnering with McLaren Racing to transform drug development with cutting-edge performance science.

Join our
talent community
What could we achieve together? Every Sanofian works on projects that truly make a difference to people’s lives.
Sign up today and discover our latest opportunities as soon as they’re available.