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Manufacturing and Supply

Manufacturing and Supply
Where the
miracles of
science
are made
a reality
for patients

Head of Site OPEX and Smart Factory

Singapore, Singapore
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At a glance

Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.

Key Accountabilities

Developing, owning, and maintaining the Site Performance Roadmap by:

  • Leading the Strategy Cascading process by working closely with internal (i.e., SLT) and external (i.e., Global Functions) stakeholders, defining site CBN’s

  • Drive internal/external benchmarking & analyses to identify performance

gaps/opportunities vs. best in class, socializing it internally and externally with key

stakeholders

  • Leading the performance & digital piece during Strat Plan and Budget, defining

performance ambition (aligned with CBN’s and GBU objectives), cascaded into

financial/operational targets across all performance dimension (e.g., +QDCI,

scorecard)

  • Developing a prioritized portfolio of initiatives (i.e., performance + modernization)

to deliver site ambition, and related: impact, resourcing, and timelines

Delivering performance ambition by leading the execution of the Site Performance

Roadmap through:

  • Focused transformation initiatives (e.g., performance boosters), when fast-paced performance breakthroughs are required

  • Standardization through SMS 2.0 ecosystem deployments enabling continuous

improvement (incl. execution support, CI standard deployment, problem solving,

OpEx method, etc.)

  • Deployment of Smart Factory solutions (incl. AI) and associated change

management to ensure value realization and expected transformation (e.g.,

Modernization Index)

  • Supplier Excellence: Own the Material & Supplier improvement initiatives (i.e.,

Supplier Excellence) & business interface of the procurement on site

Leading site performance governance by:

• Manage operational KPI management (i.e., +QDCI) including cascaded reviews

from shopfloor to SLT to track performance evolution vs. ambition

• Drive financial impact of performance actions (e.g., 3P, Sievo) ensuring value is

maximized and captured in alignment with Finance, Procurement, Operations

• Monitor overall performance trajectory vs. ambition, spot early on (risk of)

deviations and decide appropriate corrective actions

• Represent the site in above site performance reviews and forums (e.g., L4-L5)

Leading Site SMS team and developing OpEx & Digital capabilities & performance culture

• Implement Site OpEx & Smart Factory team in alignment with standard

organization

• Modernize OpEx capabilities by developing strong digital (e.g., Data Analytics, AI,

Connectivity) profiles

• Drive OpEx and Digital training in alignment with the learning administrator

• Develop strong relationships with the global OpEx community and the Global

Qualification and experience

Expected Experience:

Knowledge of main Operational Excellence techniques (e.g., Lean, Six Sigma, Agile, CI, etc.)

• Experience in transformation and change management

• Understanding of data analytics / visualization

Expected Technical skills

• Project Management

• Basics of finance and strategy

• Knowledge of main IT/Digital solutions (e.g., ERP)

• Knowledge of Manufacturing 4.0 (Paperless manufacturing operation with integrated information flow across different platform across SAP, MES, Delta V, Historian, LIMS etc)

• Knowledge and proven application of AI/Gen AI tools

Knowledge of key business & pharma processes

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Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Apply now
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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

All-in on diversity

At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

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"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan

Executive Vice President of Manufacturing and Supply

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Manufacturing & Supply Careers

Explore how Sanofi is transforming pharmaceutical manufacturing and supply chains with cutting-edge technology, digital innovation, and sustainable practices. Discover career opportunities where you can help deliver life-changing medicines efficiently and responsibly.

Learn more

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Our Formula for Success with McLaren Racing

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