Vaccines
Where
extraordinary minds
help protect half a billion people
Global Project Head - R&D Vaccines
Waltham, Massachusetts Salary Range USD 202,500.00 - 292,500.00
Who we are
Every day, 2.5 million Sanofi vaccine doses reach patients worldwide - powered by bold ideas, cutting-edge science, and passionate people like you. Across every stage — from discovery to delivery — Sanofians are shaping the future of vaccines. In global R&D hubs, exceptional offices, and state-of-the-art manufacturing sites, we’re reimagining what’s possible. But science alone isn’t enough — it’s the extraordinary minds behind it that truly make the difference.
Job Title: Global Project Head - R&D Vaccines
Location: Waltham, MA or Swiftwater, PA
About the Job
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization.
As a Global Project Head within R&D Vaccines, you will serve as the strategic leader and driving force behind the development and execution of integrated strategies and development plans for New Vaccines (NV) projects from Gate M2 through the end of development. This pivotal role places you at the intersection of science, strategy, and leadership, where you will orchestrate cross-functional collaboration to bring life-saving vaccines to patients worldwide. In this position, you will lead Global Project Teams (GPT) and sub-teams in close cooperation with R&D and non-R&D function heads, ensuring seamless alignment across all development activities. You will be accountable for project risk management and will serve as the primary communicator to governance committees, providing strategic insights and recommendations that shape project direction. Your leadership will extend beyond internal teams as you serve as a key member of the Franchise Steering Team and Brand Team, contributing to broader strategic decisions.
As the ambassador for your project both internally and externally, you will build and maintain relationships with stakeholders across the organization and with external partners, including NGOs, partner companies, academic institutions, and joint ventures. Your ability to align diverse stakeholders, navigate complex organizational dynamics, and champion project objectives will be critical to success. This role offers the opportunity to make a lasting impact on global health while leading some of the most innovative vaccine development initiatives in the industry.
Main Responsibilities:
Product Development Strategy & Execution
Contributes to creation and implementation of high-level product development strategies including Target Product/Vaccine Profile (TPP/TVP)
Hold full accountability for developing and executing project strategy from Gate M2 through licensure, ensuring alignment with organizational objectives and patient needs
Drive strategic decision-making that balances scientific innovation, commercial viability, and patient impact
Ensure project deliverables meet timelines, quality standards and regulatory requirements across all markets
Team Leadership
Structure and lead the Global Project Team, fostering a collaborative, high-performance culture
Set clear objectives, provide constructive feedback, and hold team members accountable for deliverables
Mentor and develop team members, building capabilities across the organization
Create an inclusive environment where diverse perspectives are valued and leveraged
Project Management
Deliver projects on-time, within budget, and in accordance with strategic objectives
Monitor project milestones and proactively address obstacles to maintain momentum
Ensure seamless coordination across all functional areas and geographies
Resource Management
Supervise project activities and resolve resource utilization issues across functions
Optimize allocation of budget, personnel, and materials to maximize project efficiency
Partner with functional leaders to secure necessary resources and capabilities Make data-driven decisions regarding resource prioritization and trade-offs
Strategic Planning
Translate TPP into comprehensive scope, objectives, and actionable plans
Ensure alignment across Integrated Early Global Plan (IEGP), Integrated Strategic Commercial Plan (iSCP), Clinical Development Plan (CDP), Technical Strategy Document (TSD), and Global Regulatory Plan and Strategy (GRPS)
Anticipate future needs and proactively adapt strategies to changing landscapes
Drive innovation in development approaches and methodologies
Stakeholder Management
Manage relationships with internal and external stakeholders at the executive level
Build consensus among diverse stakeholder groups with competing priorities
Navigate complex organizational dynamics to advance project objectives
Represent the project in high-level strategic discussions and governance forums
Communication
Champion project objectives, progress, and risk mitigation strategies across all organizational levels
Present to senior leadership, governance committees, and external partners with clarity and impact
Ensure transparent, timely communication of project status, challenges, and opportunities
Tailor messaging to diverse audiences, from scientific experts to business leaders
Alliance Management
Manage strategic relationships with NGOs, partner companies, academic groups, and joint ventures
Negotiate and oversee collaboration agreements that advance project goals
Ensure alignment between internal objectives and external partner expectations
Leverage external partnerships to access capabilities, expertise, and resources
Franchise Strategy
Contribute to the development of a unified R&D vision and strategic roadmap for the franchise
Integrate project strategy with broader portfolio and franchise objectives
Identify opportunities for synergies across projects and therapeutic areas
Participate in long-term strategic planning and portfolio optimization
About You
We're looking for a strategic leader who combines scientific expertise with business acumen and exceptional people leadership skills. You thrive in complex, matrixed environments and have a track record of delivering results through collaboration and influence.
Required Qualifications:
Masters of Science degree in scientific-related field of study. PhD, MD, or PharmD is preferred.
7+ years of experience in vaccine development in pharmaceutical, biotechnology, or related discipline.
Skills & Competencies:
Proven ability to lead international, cross-functional teams toward common goals
Skilled in building trust and fostering collaboration across diverse teams and cultures
Talent for inspiring and motivating others to achieve excellence
Ability to navigate ambiguity and drive clarity in complex situations
Exceptional presentation skills, capable of distilling complex information into compelling narratives
Strong negotiation skills and ability to build consensus among stakeholders with different perspectives
Commercial awareness and understanding of market dynamics
Comprehensive knowledge of vaccine development processes, regulatory requirements, and quality standards
Adaptable and resilient in the face of challenges and changing priorities
Intellectually curious with commitment to continuous learning
Passion for improving patient lives and advancing global health
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
#GD-SP
#LI-SP
#LI-Onsite
#vhd
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
Find out more about this location
Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
What does it take to protect the world from disease?
For over a century, we’ve been pioneering breakthroughs that help protect millions from diseases like polio, influenza, RSV, and more. And we’re not stopping there.
Powered by groundbreaking technologies - mRNA platforms, recombinant proteins, and AI-driven insights - we’re pushing the boundaries of science.
"I’m immensely proud of the pace of our innovation – the urgency by which our teams are working to transform the practice of medicine."
Thomas Triomphe
Executive Vice President, Vaccines
Discover more
Sanofi’s mRNA Center of Excellence
Step into the future of healthcare with Sanofi’s mRNA Center of Excellence. Discover how a global team is transforming medicine with cutting-edge mRNA technology – and explore the skills, inspirations, and breakthroughs driving this revolution. Ready to shape the future?
About Sanofi Vaccines
Explore our commitment to protecting global health through the power of vaccines. We’re building healthier communities with innovative solutions that save millions of lives each year. Dive into the future of vaccines, discover the diseases we’re tackling, and learn why vaccination is critical at every stage of life.
Join our
talent community
What could we achieve together? Every Sanofian works on projects that truly make a difference to people’s lives.
Sign up today and discover our latest opportunities as soon as they’re available.