
Les vaccins
Là où des
esprits extraordinaires
protègent un
demi-milliard de personnes
Head of Early-Stage Immunology Laboratory - Vaccines
Waltham, MassachusettsQui nous sommes
Chaque jour, 2,5 millions de doses de vaccins Sanofi sont livrées aux patients du monde entier—grâce à des idées audacieuses, une science de pointe et des personnes passionnées comme vous. À chaque étape, de la découverte à la livraison, les Sanofiens façonnent l’avenir des vaccins. Dans nos hubs mondiaux de R&D, nos bureaux d’exception et nos sites de production de pointe, nous réinventons ce qui est possible. Mais la science seule ne suffit pas—ce sont les esprits d’exception qui font vraiment la différence.
Job Title: Head of Early-Stage Immunology Laboratory - Vaccines
Location: Waltham, MA
About the Job
The Head of Early-Stage ImmunologyLaboratory reports directly to the Global Head of Early-Stage Immunology (ESI), Global Immunology (GI), Sanofi Vaccines R&D. This role provides overall strategic leadershipand direction for theimplementation, deployment and execution of immune monitoring methods used to assess specific immune responses to novel and early-stage vaccine candidates.
The Head of ESI Laboratory is accountable for ESI portfolio of immunological analyses and laboratory teams,directly supervisingLaboratory Managers andSubject Matter Expertsacross the ESI laboratory network in three sites:MarcyL’Etoile(France), Waltham and Orlando (US).
Leading the ESI portfolio of immunological analyses and the laboratory strategy across multiple sites presents ongoing challenges. The Head of ESI Laboratory is pivotal, either leading and significantly contributing to strategic initiatives that support the goals of GI and Vaccines R&D, while also challenging the status quo.
This role requires strong immunological expertise and knowledge of the New Vaccines portfolio strategy, as well as the required relevant and cutting-edge technologies, all aligned with the ESI and overall GI vision. In addition, a coordinated understanding of the Vaccines R&D organization is essential to effectively advance projects through R&D. Strong leadership is crucial to ensure cross-functional collaboration among GI, Vaccines R&D, and Pharma.
Furthermore, the Head of ESI Laboratory is responsible for talent development across the US and France, working with individuals from diverse cultural backgrounds and skill sets to achieve scientific and operational excellence.
We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.
Main Responsibilities:
Overall leadership and accountability for ESI portfolio of immunological analyses and laboratory strategy
Develop the overall ESI laboratory roadmap in collaboration with the Global Head of ESI and the Global Head of Immunology, Sanofi VaccinesR&D
Accountable for strategic and operational aspects of a wide range of immunological analyses (functional, serological, cellular, molecular) for the assessment of novel early-stage vaccine candidates and the evaluation of potential candidates
Accountable for the implementation, deployment and execution of ESI laboratory strategy across the global laboratory network
Accountable for the standardization of analyses across the ESI laboratory network, ensuring quality and reproducibility
Define the laboratory strategy with ESI Subject Matter Experts, including state-of-the-art innovative technologies and methodologies, processes and digitalization (including automation and Artificial Intelligence)
Make critical and strategic investments to maintainSanofi’s competitive advantage in investing inanalytical technologies
Define budgets (including OPEX, CAPEX, FTEs) allocated to each site
Develop the laboratory outsourcing strategy (“Make or Buy”), focusing on identifying internal core competencies, potential academic or CROs/partners, and define selection criteria
Liaise, interface and harmonize with key early-stagestakeholders, e.g., Global Antigen Design and mRNA Center of Excellence
Liaise with Head of Late-stage Clinical Testing to ensure smooth transition of analyses for phased clinical trial analyses
Guarantee the optimization and achievement of Key Project Indicators (KPIs) and overall alignment with ESI and GI strategies, providing regular reports to the Global Head of ESI
Accountable fororganization andtimely delivery of critical immune assays to formulate the vaccine image, test and establish modes of action
Provide data for the Investigational New Drug (IND)and Common Technical Document (CTD) applications
Guarantee the quality of documentation and conduct L0 regulatory dossier review
Overall leadership and accountability for ESI laboratory teams across sites
Accountable for ESI laboratory teams’ management across Marcy L’Etoile, Waltham and Orlando
Accountable for allocating resources across sites and projects based on portfolio expertise
Monitor project hours and capacity load via R&DProject Management software with support from the Function Management Office and ESI Laboratory Managers
Set and monitor individual objectives, conduct annual performance appraisal,annual career development assessment with recommendations for technical and professional training, and periodic update sessions
Master and regularly update the skills matrix in alignment with ESI and GI strategies
Identify internal core competencies and potential skill gaps
Define recruitment and development needsand coordinate with ESI Laboratory Managers to implement related action plans
Build a culture that promotes Sanofi R&D vision through a positive work environment focused on execution, efficiency, delivery, innovation and scientific rigor
Disseminate laboratory best practices and ensure consistent methodologies across sites
Provide high-level quality control of results interpretation performed by ESI Immunology project teams and Subject Matter Experts
EnsureESI Laboratory Managers strictly adhere toHSES, corporate, quality and regulatory standards,and participatein audits
Facilitate effective communication,understanding and implementation of upper management decisions across sites by appropriately cascading information
Coordinate ESI scientific communication
Shape and articulate the strategic message ESI and GI aim to convey to the global external R&D ecosystemwith the Global Head of ESI
Oversee and coordinate the contributions of ESI Immunology Leads,Subject Matter Experts and Principal Scientists, ensuringtheir publications and participations in scientific conferences and forums align with ESI and GI strategies
Shape and articulate the strategic message ESI and GI aim to convey to the global external R&D ecosystemwith the Global Head of ESI
Oversee and coordinate the contributions of ESI Immunology Leads,Subject Matter Experts and Principal Scientists, ensuringtheir publications and participations in scientific conferences and forums align with ESI and GI strategies
About You
If you are excited about leading an international team and collectively achieving laboratory excellence in Immunology and Vaccines R&D, this position is perfect for you!
Requirements
PhD in Immunology, Microbiology or related Life Sciences
10+ years of laboratory experience in Immunology and Vaccines R&D, including team management, laboratory excellence and HSES-related responsibilities
State-of-the-art techniques in Immunology
Leadership, technologyinnovation, influence and challenge,decision-making, stretch, negotiation, customer focus, deliverable-oriented and quality mindset
Excellent verbal and written communication skills in English. Proficiency in French is a plus.
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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Pourquoi nous rejoindre ?
- Nous sommes des pionniers et des innovateurs, animés par la conviction que chacun mérite un avenir en meilleure santé. Nous développons des vaccins d’excellence pour prévenir les maladies et protéger des vies.
- L’innovation nous motive. De l’IA à l’ARNm en passant par les sciences de nouvelle génération, nous repoussons les limites pour proposer les meilleurs vaccins contre les maladies infectieuses dans le monde entier.
- La croissance se fait ici. Grâce à des investissements audacieux en R&D et à des infrastructures de pointe, les Sanofians, à chaque étape du cycle de vie des vaccins, façonnent l’avenir de la santé mondiale.
- Nous faisons ce qui est juste. La durabilité et la diversité, l’équité et l’inclusion sont au coeur de notre impact positif — car les communautés diverses que représentent les Sanofiens sont aussi celles des patients que nous servons.
Qu’est-ce qu’il faut pour protéger le monde contre les maladies ?
Depuis plus d’un siècle, nous repoussons les limites de la science pour protéger des millions de personnes contre des maladies comme la polio, la grippe, le VRS et bien d’autres. Et nous ne comptons pas nous arrêter là.
Grâce à des technologies de rupture—plateformes à ARNm, protéines recombinantes et intelligence artificielle—nous allons encore plus loin dans l’innovation scientifique.

"Je suis extrêmement fier de la rapidité de notre innovation—de l’urgence avec laquelle nos équipes transforment la médecine."

Thomas Triomphe
Vice-Président Exécutif, Vaccins
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À propos de Sanofi Vaccins
Découvrez notre engagement à protéger la santé mondiale grâce à la puissance des vaccins. Nous bâtissons des communautés plus saines avec des solutions innovantes qui sauvent chaque année des millions de vies. Explorez l’avenir des vaccins, les maladies que nous combattons et l’importance de la vaccination à chaque étape de la vie..

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