R&D
Là où votre curiosité fait avancer les miracles de la science

Job Title: Senior Associate Scientist - Cell Culture Process Development (GMU)

Location: Waltham, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. 

The Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best in class manufacturing platforms to support development of life-changing advanced gene therapy products. This organization encompasses vector and cell line engineering, upstream and downstream process development, analytics, and clinical manufacturing support.  

The Cell Culture Process Development group (CCPD) is responsible for viral vector production optimization and development of next generation production platforms to support high dose therapeutic products. The group is seeking a motivated Senior Associate Scientist to join the team. 

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main  Responsibilities:  

• Support the execution and data analysis for viral vector production process development experiments  

• Work with risk group 2 infectious materials, follow safe lab procedures and maintain good laboratory practices (GLPs) 

• Contribute to technical reports and protocols  

• ·Support maintenance of facility infrastructure and management of assay reagent, control and standard inventories, as well as other support requirements 

• Collaborate with team to identify areas for improved operational excellence  

• Stay updated on new, relevant technologies and published literature to support innovation within the group 

• Support new technology evaluations to increase product yield and process understanding 

• Independently, manage personal training schedules as per established procedures  

• Communicate effectively with teams 

• Display sound technical judgement 

• Perform weekend and holiday work to support on-going lab activities 

About You

Basic Qualifications 

• Master’s degree in biological science, engineering or related discipline or a Bachelor’s degree with a minimum of 2 years of relevant experience in the life sciences, biotechnology or pharmaceutical industry 

• Aseptic skills as demonstrated by experiences with a variety of cell line maintenance and expansion

• Understanding of mammalian cell culture processes (thaw to production) 

• Knowledge and understanding of cell culture and viral vector production systems  

• Understanding of key test performance indicators, monitoring and trending of data 

• Ability to stand and work with lab bench equipment 

• Good organizational, record keeping, and communication skills 

• Motivated and self-directed with commitment to meet aggressive timelines 

• Team player, detail oriented and change-agile  

Preferred Qualifications 

• Understanding of viral process development  and drug development concepts 

• Experience of bioreactor operations (up to several hundred L scale) and cell culture processes. Ambr250 and Scivario experience preferred. 

• Ability to work under moderate supervision and function within a collaborative/team-oriented environment  

• Knowledge of Design of Experiments (DoE’s) using JMP or equivalent software

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Toujours Progresser. Découvrir l’Extraordinaire.

Rejoignez Sanofi et entrez dans une nouvelle ère de la science – où votre parcours peut être aussi transformateur que le travail que nous accomplissons. Nous investissons en vous pour que vous alliez plus loin, accélériez votre réflexion et accomplissiez ce qui n’a jamais été fait auparavant. Vous contribuerez à repousser les limites, à bousculer les conventions et à concevoir des solutions plus intelligentes pour les communautés que nous servons. Prêt·e à poursuivre les miracles de la science et à améliorer la vie des gens ? Poursuivons le progrès et découvrons l’extraordinaire – ensemble.

Chez Sanofi, nous croyons dans l’égalité des chances, sans distinction de race, de couleur, d’ascendance, de religion, de sexe, d’origine, d’orientation sexuelle, d’âge, de citoyenneté, d’état civil, de handicap, d’identité de genre ou de tout autre critère protégé par la loi.