R&D- Intrepide China - Scientist I - Suzhou

Open rank Research Scientist at Sanofi Institute for Biomedical Research (SIBR)

Sanofi is an innovative global healthcare company, driven by one purpose: we chase the miracles of science to improve people’s lives. Our teams across the world strive to transform the practice of medicine, turning the impossible into the possible for patients. SIBR is an integral part of Sanofi Global R&D and spearheading the organization's drive towards innovation through strategic partnerships with various external entities in China. We aspire to identify and leverage innovation opportunities to enrich the Global Research portfolio and ensure a sustainable growth of our R&D pipeline.

About the position

We are seeking for an exceptional, energetic, and self-motivated scientist who will be deeply involved in the scientific and experimental assessment for novel preclinical therapeutics and technology opportunities. The scope of SIBR’s research focuses on novel therapeutics in Immunology & Inflammation (I&I), Neuroinflammation, and Oncology cutting-edge technologies within, but not limited to large and small molecules, protein degraders, novel drug modalities, targeted drug delivery, and AI-assisted drug discovery.

Key responsibilities

• Culture various cell types, including primary cells (e.g., PBMCs), glial cells, iPSCs, and immortalized cell lines in appropriate conditions

• Perform cell transfection, transduction, or gene editing techniques to modulate gene expression in various cell types, enabling the study of gene function in immune responses

• Design, optimize, and validate in vitro assays to study functions of immune cells, including but not limited to co-cultures and organoids

• Lead studies on protein biochemistry and developability for large molecule drug discovery

• Employ multi-parametric techniques like flow cytometry, ELISA, and imaging…

• Lead the validation of external assets and support the search & evaluation of emerging opportunities that could potentially disrupt current treatment

• Contribute to research projects focused on therapeutics for immune-mediated diseases and neurodegenerative diseases

• Engage in communications within cross-functional and global project teams

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  Qualifications

  PhD or/and MD in biological, biomedical, and pharmaceutical sciences, candidate with demonstrated expertise in Immunology or Protein Science is highly desirable

  At least 3 years of post-degree research experience

  Extensive knowledge and research experience in therapy areas such as I&I, CNS, and oncology, as demonstrated by publications, patents, and/or licensing agreements

  Proven track-record of effective project management and problem-solving ability

  Experience in monitoring and tracking CRO conducted studies and other research activities

  Be able to effectively communicate in English and Mandarin in a highly multi-disciplinary and culturally diverse environment

  Skills for accurately reporting and interpreting experimental results, including proper documentation, report writing, and data analysis