Vaccines
Where
extraordinary minds
help protect half a billion people
Translational Principal Biostat
Who we are
Every day, 2.5 million Sanofi vaccine doses reach patients worldwide - powered by bold ideas, cutting-edge science, and passionate people like you. Across every stage — from discovery to delivery — Sanofians are shaping the future of vaccines. In global R&D hubs, exceptional offices, and state-of-the-art manufacturing sites, we’re reimagining what’s possible. But science alone isn’t enough — it’s the extraordinary minds behind it that truly make the difference.
Hiring Manager: Donghui Zhang
Location: Marcy L'etoile, France
Job type: Permanent
Grade: L2
About the job
As Translational Principal Biostatistician within our Vaccines Biostatistical Sciences team, you are the ultimate scientific owner of all statistical deliverables for your assigned translational statistical activities, bringing your quantitative passion to support cross-functional translational team, including translational strategic expert, biomarker lab scientist, immunology lead and research experts. This role is critical to our team’s success and offers exposure to a broad range of activities within Biostatistics and Programming and a broad range of stakeholders.
Ready to get started?
Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you'll help advance prevention on a global scale - and shape the future of immunization.
About Sanofi:
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enable us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Job Summary
Assume responsibility for statistical and methodological aspects as well as delivery of translational activities under technical supervision from senior staff and manager. He/she will provide critical input on the design of experiments, the analysis of translational multi-dimensional biomarkers so that accurate assessments are made for addressing fundamental translational questions and de-risk our vaccines projects, while ensuring compliance with processes expectations.
Main responsibilities:
Lead statistical aspects on translational experiments, including protocol developments.
Prepare related statistical analysis plan, including multiple panels of exploratory readouts, integrated analysis to predict immunogencity and reactogenicity. Perform statistical analysis according to SAP.
Provide statistical guidance on exploratory assay development in collaboration with internal and external labs. Ensure consistency of assay performance across different labs.
Develop the translational study reports with translational study team.
Conduct research on biomarker analyses and collaborate with key stakeholders on manuscript/publication support.
Utilize AI technologies to improve productivity while ensuring quality through the development and delivering automated statistical tools.
About you
Required Qualifications
Experience : experience in industry or institution working in translational medicine statistical or related field.
Technical Skills : Strong statistical computing skills with R expertise (required), proficiency in Python and/or SAS (a plus). Strong knowledge basis in advanced statistical methods (e.g., Bayesian statistics, linear and non-linear modelling, Machine learning methods) and able to conduct simulations and statistical analysis without programming support.
Soft Skills : Excellent problem-solving, analytical mindset and self-management; Proven interpersonal relationships and written/verbal communication skills. Ability to influence across functions in a global environment and drive organizational change
Education: PhD in Biostatistics/Statistics, Data Science; or related discipline or a Master degree with added equivalent experience.
Digital Acumen : Ability to implement automation and digital transformation initiatives
Languages: Fluent in English (required), French for on-site collaboration
Why choose us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
PursueProgress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
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Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.
Find out more about this location
Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
What does it take to protect the world from disease?
For over a century, we’ve been pioneering breakthroughs that help protect millions from diseases like polio, influenza, RSV, and more. And we’re not stopping there.
Powered by groundbreaking technologies - mRNA platforms, recombinant proteins, and AI-driven insights - we’re pushing the boundaries of science.
"I’m immensely proud of the pace of our innovation – the urgency by which our teams are working to transform the practice of medicine."
Thomas Triomphe
Executive Vice President, Vaccines
Discover more
Sanofi’s mRNA Center of Excellence
Step into the future of healthcare with Sanofi’s mRNA Center of Excellence. Discover how a global team is transforming medicine with cutting-edge mRNA technology – and explore the skills, inspirations, and breakthroughs driving this revolution. Ready to shape the future?
About Sanofi Vaccines
Explore our commitment to protecting global health through the power of vaccines. We’re building healthier communities with innovative solutions that save millions of lives each year. Dive into the future of vaccines, discover the diseases we’re tackling, and learn why vaccination is critical at every stage of life.
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