Skip to main content
Manufacturing and Supply

Manufacturing and Supply
Where the
miracles of
science
are made
a reality
for patients

Project Manager Smart Factory

Singapore, Singapore
Apply now

At a glance

Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.


The Project Manager – Smart Factory will lead the deployment and implementation of strategic Smart Factory and digital manufacturing initiatives at site. The role is responsible for managing projects end-to-end while ensuring alignment with global standards, core models, delivery frameworks and site manufacturing requirements.


In addition to project leadership, the role will serve as an End-to-End Integrated Manufacturing Systems (IMS) expert, supporting the integration of MES, Data Historian, OT connectivity, equipment and other digital manufacturing systems to enable a connected, reliable and sustainable Smart Factory environment.

Key Responsibilities


Project Management & Deployment

  • Lead and coordinate Smart Factory projects from planning through implementation and deployment, ensuring delivery in accordance with agreed timelines, scope, budget, global core models and deployment standards.
  • Own overall project planning, schedule, cost, scope, resources, risks and dependencies, ensuring appropriate mitigation and escalation where required.
  • Lead project governance and stakeholder communication across site and global teams, including regular project reviews, Steering Committee updates and decision-making forums.
  • Partner closely with users and business stakeholders to define requirements and ensure solutions meet operational needs, representing users throughout design, development, implementation and execution.
  • Drive user adoption and change management, ensuring appropriate communication, training and readiness for successful implementation of new solutions.
  • Manage project priorities and backlog, ensuring resources remain focused on the most critical deliverables and risks.
  • Establish effective project execution routines, including regular team check-ins, Progress reviews and follow-up of actions, issues and mitigation plans.

Smart Factory & Integrated Manufacturing Systems

  • Provide technical leadership for end-to-end manufacturing system integration and connectivity, including the development and oversight of required system configurations and coding.
  • Lead MES-related implementation for new products, new production setups, CAPAs, system enhancements and upgrades, ensuring right-first-time qualification and alignment with business requirements.
  • Configure, optimise and support MES, Data Historian and OT Connectivity systems, enabling effective integration between manufacturing equipment and digital systems.
  • Ensure manufacturing and equipment data required for new production setups is complete, accurate and compliant within MES and Data Historian systems in accordance with established protocols.
  • Troubleshoot complex system and integration issues to minimise downtime, maintain production continuity and continuously improve IMS performance.
  • Provide SME support for deviation investigations and root-cause analysis, supporting effective resolution of system-related issues.
  • Ensure site implementation remains aligned with global Smart Factory architecture, design guidelines and technical standards.
  • Build long-term site capability through knowledge transfer, coaching and technical upskilling on integrated manufacturing systems.
  • Participate in global Smart Factory and digital manufacturing networks, sharing lessons learned, best practices and supporting global initiatives as required.

Key Interfaces


The role will work closely with Manufacturing, Engineering, Automation, Digital/IT, Quality, Validation, MSAT, site leadership, global Smart Factory teams and external technology partners to ensure successful project execution and sustainable implementation of digital manufacturing solutions.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Apply now
Illustration of map pins on globe

Find out more about this location

Technician at work on machinery

Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

All-in on diversity

At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

Discover more

Pharmaceutical workers operating machinery

Manufacturing & Supply Careers

Explore how Sanofi is transforming pharmaceutical manufacturing and supply chains with cutting-edge technology, digital innovation, and sustainable practices. Discover career opportunities where you can help deliver life-changing medicines efficiently and responsibly.

Learn more

Pharmaceutical workers operating machinery

Accelerating Biopharma Innovation with McLaren Racing

What do Formula 1 and biopharma have in common? Speed, precision, and a drive for excellence. Discover how Sanofi is partnering with McLaren Racing to transform drug development with cutting-edge performance science.

Our Formula for Success with McLaren Racing

Join our
talent community

What could we achieve together? Every Sanofian works on projects that truly make a difference to people’s lives.

Sign up today and discover our latest opportunities as soon as they’re available.