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Vaccines

Vaccines
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extraordinary minds
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half a billion people

Head of Vaccine Research and Development Project Management

Swiftwater, Pennsylvania
Waltham, Massachusetts
Salary Range   USD 187,500.00 - 270,833.33
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Who we are

Every day, 2.5 million Sanofi vaccine doses reach patients worldwide - powered by bold ideas, cutting-edge science, and passionate people like you. Across every stage — from discovery to delivery — Sanofians are shaping the future of vaccines. In global R&D hubs, exceptional offices, and state-of-the-art manufacturing sites, we’re reimagining what’s possible. But science alone isn’t enough — it’s the extraordinary minds behind it that truly make the difference.

Job Title: Head of Vaccine Research and Development Project Management

Location: Swiftwater, PA / Waltham, MA

About the Job

Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization.

The Head of Vaccine Global Project Management leads New Vaccines R&D project management function, translating corporate strategy into executable project plans while ensuring strategic alignment, operational excellence, and delivery of complex vaccine development programs.

You will be responsible for establishing best-in-class project management standards, governance frameworks, and AI/Digital-enabled practices across the portfolio — with the ultimate goal of delivering vaccines at optimal time-to-market, within budget, and in full alignment with Sanofi's strategic objectives.

You will lead a team of 20+, with 4 direct reports:

  • Head of France Project Management

  • Head of North America & International Project Management

  • Risk & Compliance Manager

  • ·Administrative Support

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main responsibilities:

  • Set the strategic direction for Vaccines R&D project management by establishing best-in-class standards, governance frameworks, and AI/Digital-enabled practices across the portfolio

  • Drive portfolio execution by overseeing end-to-end delivery against scope, schedule, cost, and quality baselines — monitoring pipeline health and ensuring timely escalation and corrective action

  • Lead risk management and compliance across all New Vaccine projects, ensuring proactive risk identification, robust lessons learned processes, and readiness for internal audits

  • Enable effective governance through transparent Stage Gate processes, acting as TARC Secretary and key liaison between Vaccine R&D and Corporate Portfolio Management

  • Inspire and develop talent by leading a global team of 15+ project managers, fostering a culture of accountability, continuous improvement, and digital innovation

  • Oversee financial and resource planning, providing strategic input to resources and cost forecasts as well as ensuring alignment across R&D, Franchise, and Manufacturing & Supply

Dimensions / Scope:

  • Strategic Visibility: Direct interface with Vaccines R&D Leadership Team Corporate Portfolio Management, and external funding entities (BARDA and others)

  • Global Impact: Lead an international team across multiple R&D sites (4 direct reports, total of 15+ Project Managers, Functional lead for Project planning Managers in Budapest)

  • Innovation at the Forefront: Drive the integration of AI and digital tools into the future of project management for Vaccine RD project Management

  • Leadership Platform: Build and develop the next generation of project management talent within Sanofi's Vaccines organization

About You

Education:

  • MS and 12+ years of leadership experience in pharmaceutical R&D project/program management OR PhD and 8+ years of leadership experience in pharmaceutical R&D project/program management

  • Advanced degree in Project Management

  • Professional certification: PMP, Agile, or equivalent

  • Previous experience of pharmaceutical R&D project and/or portfolio management, including management responsibilities and cross functional governance contributions

  • MBA preferred but not required.

Knowledge & Technical Expertise:

  • Deep knowledge of the end-to-end vaccine/pharma development value chain (Research → Clinical → Industrialization → Registration → Launch)

  • Proven leadership in complex, global, matrixed environments

  • Expertise in PM methodologies: PMBOK, Hybrid, Agile

  • Proven expertise in R&D Risk Management

  • Business acumen and financial management in high-investment pharmaceutical contexts

  • Experience in digital planning tool or AI/digital solution rollout

Key Skills & Abilities:

  • Strategic & Tactical Thinking — Translates strategy into execution frameworks

  • People Leadership — Mobilizes global teams and inspires action

  • Influence & Stakeholder Management — Communicates effectively at operational and executive levels

  • Change Management — Guides teams through transformation with confidence

  • Decision-Making & Prioritization — Acts with clarity under pressure

  • Coaching & Development — Builds capability through structured support

  • Cross-Functional Agility — Operates effectively in multicultural, worldwide matrix environments

  • Digital/AI Mindset — Anticipates and drives innovation in project management

  • Languages: English fluent (required); French fluent (preferred)

Why Choose Us? 

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.

Apply now
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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

What does it take to protect the world from disease?

For over a century, we’ve been pioneering breakthroughs that help protect millions from diseases like polio, influenza, RSV, and more. And we’re not stopping there.

Powered by groundbreaking technologies - mRNA platforms, recombinant proteins, and AI-driven insights - we’re pushing the boundaries of science.

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"I’m immensely proud of the pace of our innovation – the urgency by which our teams are working to transform the practice of medicine."

Thomas Triomphe

Executive Vice President, Vaccines

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Sanofi’s mRNA Center of Excellence

Step into the future of healthcare with Sanofi’s mRNA Center of Excellence. Discover how a global team is transforming medicine with cutting-edge mRNA technology – and explore the skills, inspirations, and breakthroughs driving this revolution. Ready to shape the future?

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About Sanofi Vaccines

Explore our commitment to protecting global health through the power of vaccines. We’re building healthier communities with innovative solutions that save millions of lives each year. Dive into the future of vaccines, discover the diseases we’re tackling, and learn why vaccination is critical at every stage of life.

Learn more

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