Associate Director Quantitative Systems Pharmacology (QSP)

About the Job
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

The Translational Disease Modeling (TDM) group at Sanofi is seeking to hire a highly talented Quantitative Systems Pharmacology (QSP) modeling scientist to support its R&D portfolio. Modeling efforts represent key biological processes of the pathophysiology and a drug’s mechanism of action to enhance the understanding of disease and therapeutic response. QSP-model based simulations allow prediction of drug efficacy in virtual patients. The successful candidate will be working within a dynamic, multidisciplinary environment to provide support for strategy and decision making in drug research and development. The position is based in Cambridge, MA.

• Design, build, and apply QSP modeling approaches to support decision making

• Interface with project team to identify opportunities, and to develop and implement innovative mechanistic modeling strategies

• Communicate modeling predictions to key stakeholders

• Collaborate with internal and external partners (CROs, consultants and academic collaborators) to support internal QSP efforts

• Identify and interpret preclinical and clinical data critical for model development and refinement

• Maintain state-of-the art knowledge of relevant modeling approaches and techniques

• Contribute to abstracts and manuscripts

About You

• Earned Ph.D. (in Biomedical Engineering, Applied mathematics, Systems Biology/Pharmacology or related field) and 5+ years of mathematical modeling & simulation experience within the pharmaceutical industry

• Track record of productivity, with evidence of independence in leading scientific projects

• Hands-on experience with programming languages like Matlab/R/Julia (Matlab preferred)

• Experience in differential equation- based models and parameter optimization approaches

• Understanding of theory, principles and statistical aspects of mathematical modeling and simulation

• Good understanding of cell biology and physiology, as well as the basic principles of pharmacokinetics and pharmacodynamics

• Strong project management skills including organization, time management and follow-up

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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