Portfolio Lead – Fabry and Gaucher
Cambridge, Massachusetts Regular Posted on Jan. 30, 2026 Closing on Mar. 30, 2026 Salary Range USD 206,250.00 - 297,916.66Job Title: Portfolio Lead – Fabry and Gaucher
Location: Cambridge, MA
About the Job
Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.
Sanofi Rare Diseases are on a mission to modernize a successful 30+ year rare disease business model so that we are positioned to deliver new therapies over the next 5 years and maintain our leadership position in the pharma environment. The model we are deploying is not only new to Sanofi, but new to our pharma peers. Success of this mission will mean modernizing a talent dense team that can make faster decisions closer to the customers we serve.
The Portfolio Lead - Fabry & Gaucher will serve as a strategic leader and visionary for our Gaucher & Fabry products, driving enterprise-wide brand strategy with a customer-centric approach. This senior executive will be accountable for defining and executing product positioning and comprehensive strategic roadmaps based on deep market intelligence, patient journey insights, and the transformative value that products and services deliver in improving patient outcomes. This leader will provide strategic direction across our GTM models and will lead an Associate Director of Marketing, fostering talent development and organizational capability building.
About Sanofi:
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities:
Across the Rare Disease Nation, we have launches over the next several years and this role will be expected to provide senior-level product strategy leadership and expertise across all launches; one team, common goals, single mission. In the newly formed organization, this role will report to the Head of Marketing.
Strategic Leadership & Vision: Architect and drive the long-term strategic vision for Gaucher & Fabry brands, establishing enterprise-wide priorities that align with organizational objectives and market opportunities. Provide thought leadership that shapes the future direction of the rare disease portfolio.
Brand Portfolio Management: Lead comprehensive brand planning, budgeting, KPI development and tracking, forecasting, and financial stewardship across multiple brands. Drive strategic resource allocation decisions and investment prioritization to maximize portfolio value and market impact.
Cross-Functional Leadership & Influence: Serve as the primary strategic partner and liaison with global GBL, country teams, PSS, patient marketing, Account Engagement marketing, and health system marketing teams. Lead and influence senior-level stakeholders across the organization, driving alignment on critical brand decisions and strategic initiatives.
Market Intelligence & Strategic Insights: Develop and synthesize sophisticated insights on disease areas, market dynamics, and competitive landscapes using comprehensive US and global data sources. Transform complex data into actionable strategic recommendations that drive competitive advantage.
Customer & Market Strategy: Orchestrate insights gathering across marketing channels, customer segments, and digital platforms. Lead the development of deep customer understanding to articulate compelling value propositions that address unmet needs in the rare disease category.
Competitive Strategy & Market Positioning: Continuously monitor and analyze the competitive environment, pipeline activities, and market trends. Develop proactive strategies to address competitive threats and capitalize on market opportunities, ensuring organizational readiness for market shifts.
Patient Journey & Market Development: Create comprehensive, end-to-end patient journey strategies, including innovative approaches to patient identification, diagnosis acceleration, and treatment optimization. Drive market development initiatives that expand access and improve patient outcomes.
Commercial Strategy Execution: Develop and execute sophisticated commercial brand strategies informed by market intelligence, customer insights, and competitive analysis. Build adaptive strategies that can be rapidly deployed in response to competitive entrants and market dynamics.
Governance & Organizational Alignment: Lead cross-functional governance forums and strategic planning sessions to ensure enterprise-wide alignment. Drive organizational consensus on strategic priorities and provide strategic input to support accurate product demand forecasts and business planning.
Financial Stewardship: Manage substantial brand marketing budgets with strategic oversight. Provide senior-level input on annual planning processes, ensuring alignment with global marketing strategies, regulatory requirements, and business objectives. Drive ROI optimization across all brand investments.
Launch Excellence: Lead launch readiness initiatives with strategic oversight, including competitive assessment, target product profile (TPP) development, market access strategy, and comprehensive pre-launch planning. Ensure organizational preparedness for successful product introductions.
Team Leadership & Development: Provide strategic leadership and mentorship to an Associate Director of Marketing, fostering professional growth, strategic thinking capabilities, and leadership development. Build organizational capability and talent density within the marketing function.
About You
Education: Bachelor's degree in marketing, business, technology, or life sciences required; MBA or advanced degree strongly preferred
Experience: 12+ years of progressive marketing, sales, or insights & analytics experience in the pharmaceutical or biotechnology industry, with demonstrated success in senior leadership roles driving strategic initiatives
Leadership Excellence: Proven track record of leading and developing high-performing teams, with experience managing marketing professionals and driving organizational capability building
Strategic Acumen: Exceptional strategic decision-making capabilities with a history of innovation, complex problem-solving, and successfully navigating ambiguous situations without clear precedent. Demonstrated ability to think strategically while executing tactically
Cross-Functional Leadership: Extensive experience working within large-scale, complex multidisciplinary organizations with proven ability to influence and drive alignment across senior stakeholders without direct authority
Launch Strategy Expertise: Deep expertise in product and launch strategy development and execution, with demonstrated success in building and growing brands in competitive markets
Rare Disease or Specialty Experience: Experience in rare disease, specialty therapeutics, or complex treatment paradigms strongly preferred
Global Perspective: US, Global, and Ex-US experience preferred, with understanding of diverse market dynamics and regulatory environments
Executive Presence: Strong executive presence with ability effectively with C-suite leaders, external stakeholders, and key opinion leaders
Travel: Ability to travel up to 25% within the US and internationally as needed
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
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