Biomarker and Precision Medicine Lead

Job Title: Biomarker and Precision medicine Lead

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate Progress.

Sanofi is seeking an outstanding Translational Medicine Lead with scientific expertise in immunology to develop translational medicine strategies.  This exciting position is in the Biomarker & Translational Medicine group, focusing on the Immunology therapeutic area.  Immunology is a high priority therapeutic area for Sanofi with a robust pipeline of molecules representing diverse therapeutic modalities that modulate a broad array of targets. The core responsibility for this position is the strategic development and implementation of translational medicine plans for projects, including identifying biomarkers that predict patient clinical response, demonstrate molecular activity, and/or correlate with clinical efficacy/safety endpoints.  The individual will be a key member of global research and development project teams.  Collaborative interactions with basic research scientists, clinicians, modeling and simulation experts, bioinformatics scientists, and biomarker experts are critical to success in the role. 

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• Develop translational medicine strategy for research and development projects, including identification of biomarkers for patient selection, pharmacologic effect, and clinical efficacy/safety

• Collaborate with multidisciplinary functions to design and lead the implementation of informative biomarker strategies in clinical studies using a broad range of approaches, including data science, omics, and bioimaging

• Have deep scientific understanding of the relevant pathways and diseases in immunology, including relating abnormalities in biological pathways to manifestations and markers of human disease, resulting in clinical biomarker strategies for projects

• Review and critically interpret results, including internal and external clinical and non-clinical data

• Collaborate effectively with global team members and managers from various disciplines; serve as expert and internal consultant on assigned area and liaise with partners on projects

• Lead translational medicine sub-teams for projects, coordinating efforts for biomarker identification and use

• Identify optimal platforms and methodologies for generation of biomarker data

• Ensure execution of biomarker studies to meet project timelines and budgets

• Engage external key opinion leaders on projects and potential collaborations

• Present data and plans in appropriate meetings (internal and external)

Key Internal/External Relationships:

• Internal contacts: Laboratory research scientists, therapeutic area clinicians, biomarker assay and bioanalysis experts, clinical pharmacologists, clinical project team, project head, bioinformatics scientists, biostatisticians, toxicologists, regulatory affairs experts  

• External contacts: Clinical and basic science external expert consultants, biomarker vendors, health authority representatives

About You

• Earned MD, PharmD, or PhD with 5+ years of experience in translational or clinical research

• Expertise in immunology and/or inflammatory diseases or related field

• In-depth understanding of identification and utilization of biomarkers in drug development

• Experience in translating the biomarker strategy from research to clinical drug development and/or research

• Experience in implementing reverse translation approaches to bridge the translational gap

• Scientifically inquisitive, energetic, proactive, and driven to actively take part in scientific and clinical study challenges

• Excellent communication skills and the ability to work and communicate cross-functionally with a common goal in mind

• Experience with bioinformatics and computational methods for analysis is highly preferred

• Understanding of biomarker assay development for clinical use also preferred

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.