Mass Spectrometry Principal Scientist

About the Job

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Sanofi is seeking a highly motivated mass spectrometrist to join our analytical group as a principal scientist.  The group is part of the synthetic platform within Global CMC Development that is striving to become an industry leader in the development of transformative medicines.   

The primary responsibility of this position is to provide analytical support to the chemistry teams.  In this role, you will be responsible for the structural characterization and quantitation of synthetic small molecules using LC/MS and GC/MS as the primary techniques.  This position is onsite and is based in Cambridge, Massachusetts, USA.

Key Responsibilities

• Provide identification and structural characterization of unknown impurities and degradants of synthetic small molecules.

• Develop LC/MS and GC/MS based quantitation methods for small molecule quantitation and be responsible for validating them when necessary

• Develop effective collaborations with other analytical chemists within the group and other scientists in project teams

• Introduce innovative analytical approaches to facilitate optimal decision-making

• Generate technical reports independently

• Share knowledge and experience of analytical method development for synthetic molecules

• May serve as a project lead

About you

Basic Qualifications

• A PhD in analytical chemistry or related field with a minimum of 4 years experience in the pharmaceutical/biotech industry

• Expertise in the operation of LC/MS and GC/MS

• Extensive experiences in method development using LC/MS and GC/MS

• Experiences in analytical method validation

• Good communications skills

Preferred Qualifications

• In-depth understanding of separation principles of LC, GC and ion mobility

• In-depth understanding of the principles of tandem mass spectrometry and state-of-the-art ion dissociation techniques

• Familiarity with the operation of LC/MS systems from multiple manufacturers

• Familiarity with software assisting compound identification by LC/MS and GC/MS

• Demonstrated ability to solve complex problems with advanced LC/MS techniques

• Demonstrated expertise in chromatography method development and trouble shoots

• Knowledge of QbD concepts, specification setting, and cGMP, with experience in contributing to regulatory submission

• Communicates effectively in individual and group settings and collaborate effectively in a multi-disciplinary team environment

• Demonstrated project management skills

• Consistent record of collaboration with scientists and other stake-holders at external enterprises

• Advanced scientific network in the industry and academia

• Record of patents and publications

• Record of adhering to and promoting lab safety practices

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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