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Director Global Market Access & Pricing, frexalimab

Cambridge, Massachusetts Regular Posted on   Oct. 16, 2026 Closing on   Nov. 30, 2026 Salary Range   USD 178,500.00 - 257,833.33
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Job title: Director Global Market Access & Pricing, frexalimab

  • Location: Cambridge, MA

About the Role


Frexalimab is a potential first-in-class anti-CD40L antibody that could change the course of MS by addressing remaining unmet need. With compelling Phase 2 efficacy data and a comprehensive Phase 3 program underway, including 3 clinical studies for RMS and nrSPMS, the program is at a critical point. MS is expected to be the first indication in a broader multi-indication program spanning immunology and metabolic diseases.


The frexalimab Global Market Access & Pricing director role provides an exceptional opportunity to make a tangible difference in patients' lives by contributing to the pricing and market access strategy across RMS and nrSPMS indications and supporting its end-to-end execution. The stakes for this role are high. In a highly competitive MS landscape, frexalimab's ambition to redefine the standard of care demands novel approaches and best-in-class methodologies to unlock its full pricing and access potential in RMS and nrSPMS. Critically, while this role focuses on MS, the strategic choices made now in MS will set the tone and trajectory for potential follow-on indications, amplifying the long-term impact of this role well beyond the initial launch.


This is a highly collaborative role, requiring strong cross-functional partnership with Commercial, Medical, Clinical, Evidence for Access, Global Pricing, Biostatistics, Regulatory Affairs, Public Affairs teams, as well as country teams. You'll be part of a high-performing team that values strategic thinking and an unwavering focus on patient access.


This position sits within the Global Market Access & Pricing Neurology Team, which is part of the Specialty Care Global Market Access organization, where collaboration, patient-centricity, and scientific rigor drive everything we do. Our mission is to enable timely access for patients while securing value recognition by external stakeholders, including payers.


Join the team transforming care for people with immune challenges, rare diseases, cancers, and Specialty Care neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.


About Sanofi


We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities


  • Drive development of key pricing & market access deliverables, including the market access plan, payer value story, global pricing policy informed by pricing research and other data points, contracting strategy, country launch sequencing, negotiation guide, and objection handler
  • Play a key role in shaping the MS ecosystem in collaboration with Commercial, Medical, Public Affairs, other global business partners and countries to drive payer value recognition of frexalimab by the time of launch, aiming for sustainable access to innovation
  • Generate actionable payer insights through primary research, payer advisory boards, or other platforms to continuously pressure test and refine frexalimab's value proposition and ensure pricing and access strategies are grounded in robust market understanding across markets
  • Contribute to the development of frexalimab’s pricing and access MS strategy and scenario planning, in partnership with the Global Brand / Global Project Teams and countries, taking a holistic approach to optimize brand value
  • Champion the adoption of digital and AI-enabled tools within the payer access strategy and execution for frexalimab, partnering with relevant internal stakeholders to identify opportunities that enhance payer engagement, value messaging, and decision-making support
  • Ensure relevant input and engagement from countries, partnering closely with country Market Access leads to co-develop global deliverables optimally and on time to support local payer negotiations
  • Work with Evidence for Access, Medical, and relevant functions to secure evidence generation plans, prioritization, and deliverables thatrobustly support access and pricing objectives
  • Maintain deep knowledgeof the MS and payer ecosystems – scientific/clinical developments, competitive landscape, payer dynamics, and healthcare policy changes – to proactively identify market access opportunities and threats and inform frexalimab’s market access and pricing strategy.

About You


  • Bachelors degree minimum, advanced degree preferred
  • Minimum 7 years of pharmaceutical/biotech industry experience, with an accomplished track record in pricing and market access, preferably in multiple sclerosis, neurology, or similar complex therapeutic areas
  • Experience working across different payer archetypes, with deep knowledge of the US market and healthcare system
  • Innovative mindset with ability to develop creative solutions to complex problems
  • Proven track record of developing and executing payer shaping initiatives in challenging reimbursement environments
  • Strong analytical skills, including pricing expertise, with ability to translate clinical information and messages into clear payer access strategies and recommendations
  • Flexibility and demonstrated ability to work across multiple projects and priorities
  • Demonstrated relationship building at all levels of the organization and across geographies; experience working collaboratively and cross-functionally 
  • Outstanding written and oral communication skills, with the ability to deliver clear and concise messages based on complex information
  • Strong business acumen, analytical and financial skills to evaluate investment strategies; comfortable with product forecast and P&L
  • Fluent in English, both written and oral

Why Choose Us


  • Bring the miracles of science to life alongside a supportive, future-focused team. 
  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 
  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 
  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. 


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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.

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