Downstream Purification Scientist- Vaccines

Job Title: Downstream Purification Scientist- Vaccines

About the Job

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

The Downstream Process Development, MSAT department is responsible for

• Seasonal strain changes for recombinant protein Influenza & Covid Vaccine

• Continuous Process development and yield improvement

• Scale up and scale down model

• Tech transfer

• Manufacturing support

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• Leading the development of robust downstream unit operations and processes that can be scaled up to manufacturing scales.

• Executes purification experiments including automated or high-throughput chromatography (AKTA platform), filtration, clarification/ depth filtration, column packing, and tangential flow filtration independently based on expert knowledge of protein purification and analysis with an in-depth understanding of all modes of chromatography. Makes detailed observations, analyzes data, and interprets results. Exercises technical discretion in the design, execution, and interpretation of experiments that contribute to projects.

• Using scientific principles and professional practices to solve a wide range of problems creatively and practically.

• Representing the team in cross-functional and/or cross-site interactions

• Serving as a subject matter expert both inside and outside the company. Act as an advisor to the management and assist with the professional development efforts of the team.

• Preparing technical protocols, reports and externally presenting to health authorities

• Introducing novel purification technologies to the team and maintaining a high level of professional expertise through familiarity with scientific literature

• Responsible for coaching junior scientists and support laboratory operations.

About You

BASIC QUALIFICATIONS:

• Masters or Doctorate (Ph.D.) degree in Biochemistry, or a related field, with at least 5+ (MS), or 2+ (PhD) years of experience.

• Skilled with protein chemistry, protein functional structural analysis.

•  Experienced in variety of separation techniques.

• Strong hands-on experience in protein purification and characterization.

• Excellent oral and written communication skills.

• Demonstrate ability to function as a major investigator, generating original technical ideas and development strategies.

PREFERRED QUALIFICATIONS:

• Experience with high throughput technologies, automation platforms and data management.

• Efficiency in molecular modeling software is desirable.

• Expert user of AKTA chromatographic instruments (such as AKTA Avant, AKTA Pure or similar).

• Strong understanding of analytical techniques such as HPLC, ELISA, CESDS, Circular Dichroism etc.

• Experience in solving complex problems where analysis requires an in-depth evaluation of various factors.

• Experience in quality control tracking systems including change controls, deviations, CAPA, root cause analysis, etc.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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