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Senior Scientist
Waltham, Massachusetts Permanent Date posted Jul. 24, 2024About the Job
We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.
Main responsibilities:
The primary responsibilities of the Senior Scientist, Virology will be to support covid vaccine projects by establishing a SARS-CoV-2 pseudoviral production lab. Ensure the generation of materials meets the quality requirements and suitable for neutralization assays. Optimize and develop additional pseudovirus capability as needed by the project and other departments in the organization. This position provides key contributions to established vaccine systems as well supporting new technologies in vaccine progression. S/he/they is an accomplished Virologist and to actively take part in training junior staff and providing experimental strategy to senior team members.
Scientific support licensed vaccines and novel vaccine portfolio progression (75%)
S/he/they will independently plan, design and execute experimentation within the scope of the projects, to meet the program objectives and demonstrate a willingness to implement new technologies and protocols, as needed.
Demonstrate technical proficiency with the ability to problem solve in a broad array of experimental protocols.
Present concise scientific presentations in line with project objectives
Guarantees the quality of data generation and documentation required for the project.
Generation and management of external contracts with CROs and academic partners.
Support efficient collaboration and alignment with other groups and functions to maximize value added.
Present concise scientific presentations in line with project objectives
Local Subject Matter Expert: Develops and Provides Scientific Expertise (15%)
Contributes to innovation and cross-functional and/or external collaborations.
Acts as a catalyser to promote scientific visibility on technological aspects (publications, communications at conferences)
Communicates efficiently of project progression to upper management as needed.
Fosters training and mentoring of junior staff members.
Communication (5%)
Ensures regular communication with the main clients: definition of the needs, harmonization of methods, efficient transfer of assets.
S/he/they communicate their own research results and those of the team/sub-team at internal meetings
Acts as a catalyser to promote scientific visibility on technological aspects (publications, communications at domestic conferences).
Keeps up to date with scientific, development and business aspects related to the portfolio
Ensures efficient reporting of his/her/their Unit activities.
Is accountable to report any delays, technical issues in team/sub-team(s), to the Operational Management and for proposing solution/scenario to mitigate project impacts.
HSE /Quality Responsibilities (5%)
Actively take part in the training.
Comply with the company safety policies and HSE to minimize risk to self, others and the environment, consistent with HSE policies, community and industry standards.
Identify and help to improve best practices in HSE operations.
Document all work appropriately in electronic tools following the required quality systems
Manage laboratory support activities such as maintaining equipment under GLP quality standards and ordering lab supplies.
Responds promptly to all health and safety concerns or incidents and completes the appropriate documentation in a timely manner
Ensures that critical incidents and accidents are reported to the appropriate authorities & manager
About You
Experience: Previous experience working in the industry, preferably in vaccinology or equivalent discipline.
Skills:
Extensive hands-on expertise in Virological techniques: virus amplification, titration assay, virus like particle generation/characterization, pseudovirus generation/characterization, and neutralization assays
Molecular Biology applications: PCR, cloning, site-directed mutagenesis, RNA extraction, RT-PCR, Sequencing analysis
Ability and willingness to train others on cross functional assays as well as develop new methodologies as needed
Cell culture aseptic techniques
Knowledge and experience with automated or semi-automatic platforms in assay use is a plus
Experience in working in regulated environment with quality systems and knowledge of ISO or GLP quality standards.
Hands-on experience with scientific software for advanced data analytics and visualization is a plus: Geneious, snap gene, Prism, Tableau, or Sequencher
Experience working in an agile and fast-paced environment
Displays a high degree of integrity, decides and acts in the best interest of the Company
Proficient interpersonal, communication, presentation, good record keeping and attention to detail
Resourcefulness: ability to find tactical solutions to challenges
Strongly results-oriented and data-driven, track record of delivery against challenging viral vaccine targets with aggressive timelines
Performance-oriented with ability to deliver against extremely aggressive timelines
Education: PhD: +3 yrs; MSc: +5 yrs; BSc: +8yrs in Virology or related field
Languages: English
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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Pursue progress. Discover extraordinary.
Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
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